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Takotsubo cardiomyopathy: an Australian single centre experience with medium term follow up

H Samardhi1, O C Raffel, M Savage

  • 1Cardiology Program, The Prince Charles Hospital, Brisbane, Queensland, Australia.

Internal Medicine Journal
|March 15, 2011
PubMed

Insights

Takotsubo cardiomyopathy (TC) is a reversible heart condition often triggered by stress. While generally having low complication and recurrence rates, it can cause significant in-hospital illness in some patients.

Area of Science:

  • Cardiology
  • Internal Medicine

Background:

  • Takotsubo cardiomyopathy (TC) is increasingly recognized in patients presenting with acute coronary syndrome features.
  • This study details a single-center experience with TC, including medium-term follow-up.

Purpose of the Study:

  • To analyze the clinical presentation, complications, and outcomes of Takotsubo cardiomyopathy.
  • To evaluate medium-term follow-up data for patients diagnosed with TC.

Main Methods:

  • Retrospective analysis of 52 consecutive patients diagnosed with TC.
  • Inclusion of clinical data, echocardiograms, and cardiac MRI for analysis.

Main Results:

  • The cohort was predominantly female (51/52 patients), with stress preceding presentation in 71%.
  • Common symptoms included chest pain (83%); ECG changes like ST elevation (40%) and T wave inversion (44%) were frequent.
  • In-hospital complications occurred in 21% of patients, including cardiogenic shock and cerebrovascular events. Left ventricular ejection fraction improved significantly from presentation (mean 47%) to follow-up (mean 63%).

Conclusions:

  • Takotsubo cardiomyopathy is a reversible condition with low rates of long-term complications and recurrence.
  • However, a significant proportion of patients experience considerable in-hospital morbidity.
Abstract

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