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Localization of Plasma Membrane and Intracellular Neuronal Nicotinic Acetylcholine Receptors Using Quantitative Imaging in Mammalian Cells
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Structural characterization and agonist binding to human α4β2 nicotinic receptors

Corrie J B daCosta1, R Michel Sturgeon, Ayman K Hamouda

  • 1Department of Biochemistry, Microbiology, and Immunology, University of Ottawa, 451 Smyth Rd., Ottawa, Ontario, Canada K1H 8M5.

Biochemical and Biophysical Research Communications
|March 15, 2011
PubMed
Summary

Researchers structurally characterized the human α4β2 nicotinic acetylcholine receptor, revealing similarities and differences compared to the Torpedo receptor. This provides new insights into neuronal nicotinic acetylcholine receptor structure and function.

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