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Related Experiment Video

Updated: Jun 3, 2026

A Simple Non-invasive Method for Temporary Knockdown of Upper Limb Proprioception
07:42

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Published on: March 3, 2018

The Koebner phenomenon.

Lior Sagi1, Henri Trau

  • 1Department of Dermatology, Chaim Sheba Medical Center, Tel-Hashomer 52621, Israel. lior115@gmail.com

Clinics in Dermatology
|March 15, 2011
PubMed
Summary
This summary is machine-generated.

The Koebner phenomenon causes new skin lesions after injury in conditions like psoriasis and vitiligo. Its exact cause remains unclear, involving factors like cytokines and immune responses.

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Area of Science:

  • Dermatology
  • Immunodermatology

Background:

  • The Koebner phenomenon, described in 1876, is the development of skin lesions at sites of injury.
  • This response is observed in various dermatoses, including psoriasis, vitiligo, and lichen planus.

Purpose of the Study:

  • To review the clinical features, triggers, and proposed mechanisms of the Koebner phenomenon.
  • To highlight the range of skin diseases exhibiting this isomorphic response.

Main Methods:

  • Literature review of clinical manifestations and proposed pathogenesis.
  • Analysis of provocative factors and associated dermatological conditions.

Main Results:

  • The Koebner phenomenon presents as new lesions following cutaneous trauma in affected individuals.
  • Potential pathogenic factors include cytokines, stress proteins, adhesion molecules, and autoantigens.
  • Numerous diseases, beyond psoriasis, demonstrate this isomorphic response.

Conclusions:

  • The Koebner phenomenon is a significant dermatological response with diverse clinical implications.
  • Understanding its pathogenesis is crucial for managing associated skin conditions.