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Related Experiment Video

Updated: Jun 3, 2026

Performing and Processing FNA of Anterior Fat Pad for Amyloid

Performing and Processing FNA of Anterior Fat Pad for Amyloid

Published on: October 30, 2010

Pathologic implications of prostatic anterior fat pad.

Jeongyun Jeong¹, Eun Yong Choi, Dong I Kang

¹Section of Urologic Oncology and Dean and Betty Gallo Prostate Cancer Center, The Cancer Institute of New Jersey/Robert Wood Johnson Medical School, New Brunswick, NJ 08903, USA.

Urologic Oncology

|March 15, 2011

Summary

This summary is machine-generated.

Prostate cancer staging can be improved by examining the prostatic anterior fat pad (PAFP). This fat pad contains lymph nodes in over 11% of patients, and its analysis can upstage cancer, aiding treatment decisions.

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Published on: August 1, 2025

Area of Science:

Urology
Pathology
Oncology

Background:

Lymph node status is critical for prostate cancer staging and treatment.
The prostatic anterior fat pad (PAFP) is often excised during robot-assisted radical prostatectomy (RARP).

Purpose of the Study:

To investigate the role of the PAFP in the pathologic staging of prostate cancer.
To determine the prevalence of lymph nodes and metastatic cancer within the PAFP.

Main Methods:

Pathologic analysis of PAFP excised from 258 patients during RARP.
Evaluation for lymphoid tissue and metastatic prostate cancer.
Retrospective chart review for patient data.

Main Results:

Over 11% of PAFPs (30/258 patients) contained lymph nodes.
Higher preoperative PSA levels were observed in patients with PAFP lymph nodes.
Metastatic prostate cancer was found in 3/30 patients with PAFP lymph nodes; one had negative pelvic nodes and remained recurrence-free at 2 years.

Conclusions:

The PAFP contains lymph nodes in a significant subset of patients undergoing RARP.
PAFP excision and analysis can lead to prostate cancer upstaging.
Routine consideration of PAFP excision and pathologic analysis is recommended for improved prostate cancer staging.