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Moyamoya disease in early infancy: case report and literature review

Catherine Amlie-Lefond1, Osama O Zaidat, Sean M Lew

  • 1Department of Neurology, Medical College of Wisconsin, Milwaukee, WI, USA. KLefond@mcw.edu

Pediatric Neurology
|March 15, 2011
PubMed

Insights

Moyamoya disease, a rare infant condition, can cause stroke. Prompt revascularization surgery offers a successful treatment for affected infants, even at a very young age.

Area of Science:

  • Neurology
  • Pediatric Neurology
  • Cerebrovascular Diseases

Background:

  • Moyamoya disease is a progressive cerebrovascular arteriopathy.
  • It involves stenosis of major cerebral arteries and collateral vessel formation.
  • Infantile moyamoya disease is rare but carries significant risks.

Observation:

  • A 2-month-old boy presented with stroke symptoms.
  • The stroke was secondary to moyamoya disease.
  • This represents the youngest reported patient with moyamoya disease.

Findings:

  • The infant patient underwent successful revascularization surgery at 3 months old.
  • Literature review indicates a high risk of ischemic events in infants with moyamoya disease.
  • Early surgical intervention appears to yield positive outcomes.

Implications:

  • Prompt revascularization surgery is a viable and effective treatment for infantile moyamoya disease.
  • Early diagnosis and intervention are crucial for preventing further ischemic events.
  • This case highlights the importance of considering moyamoya disease in infants presenting with stroke.

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