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Preparation of Highly Porous Coordination Polymer Coatings on Macroporous Polymer Monoliths for Enhanced Enrichment of Phosphopeptides
Published on: July 14, 2015
Preparation and application of hydrophilic monolithic columns
Zhengjin Jiang1, Norman William Smith, Zhenghua Liu
1Department of Pharmacy and Guangdong Province Key Laboratory of Pharmacodynamic Constituents of Traditional Chinese Medicine & New Drug Research, Jinan University, Guangzhou, China. jzjjackson@hotmail.com
Journal of Chromatography. A
|March 15, 2011
Summary
Hydrophilic interaction chromatography (HILIC) monolithic columns are a growing trend. This review covers their preparation, applications, and separation mechanisms over the last decade.
Area of Science:
- Analytical Chemistry
- Chromatography
Background:
- Hydrophilic interaction chromatography (HILIC) is gaining prominence.
- Research is active in HILIC separation mechanisms, column techniques, and applications.
Purpose of the Study:
- To provide an overview of hydrophilic monolithic column preparation and applications in HILIC.
- To review the separation mechanisms of various hydrophilic monolithic stationary phases.
Main Methods:
- Literature review of HILIC monolithic columns published in the past decade.
- Analysis of preparation methods, application data, and separation mechanisms.
Main Results:
- Hydrophilic monolithic columns are a significant trend in HILIC due to their properties.
- The review covers diverse preparation strategies and applications.
- Separation mechanisms of different monolithic stationary phases are discussed.
Conclusions:
- Hydrophilic monolithic columns offer advantages for HILIC separations.
- This review consolidates recent advancements in the field.
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