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Nocturnal enuresis in children: prevalence, correlates, and relationship with obstructive sleep apnea
Miao Shang Su1, Albert M Li, Hung K So
1Department of Respiratory Medicine, Wenzhou Medical College Affiliated Second Hospital-Yuying Children's Hospital, Zhejiang, People's Republic of China.
Insights
Nocturnal enuresis (NE) prevalence was 4.6% in primary school children, with boys affected more. NE was not linked to obstructive sleep apnea (OSA) overall, but increased with OSA severity in girls.
Area of Science:
- Pediatric Sleep Medicine
- Urology
- Public Health
Background:
- Nocturnal enuresis (NE) is common in children.
- Obstructive sleep apnea (OSA) is increasingly recognized in pediatric populations.
- The relationship between NE and OSA requires further investigation.
Purpose of the Study:
- To determine the prevalence and associated factors of NE in primary school children.
- To compare NE prevalence in children with and without OSA.
- To explore the association between OSA severity and NE.
Main Methods:
- A community-based study involving 6147 children aged 6-11 years.
- Parental questionnaires collected data on sleep symptoms, demographics, and medical history.
- Polysomnography (PSG) was performed on a subset of children screened for OSA risk.
Main Results:
- The overall prevalence of NE was 4.6%, higher in boys (6.7%) than girls (2.5%).
- NE prevalence was not significantly higher in children with OSA.
- In girls, NE prevalence increased with OSA severity; boys with NE had longer deep sleep duration.
Conclusions:
- NE prevalence in primary school children is associated with sex.
- A link between NE and OSA severity was observed in girls.
- Sleep-related symptoms and sex are significant correlates of NE.
Objectives:
To examine the prevalence and correlates of nocturnal enuresis (NE) in primary school children, and to compare the prevalence of NE in children with and those without obstructive sleep apnea (OSA).
Study Design:
Parents of children aged 6-11 years completed a questionnaire eliciting information on sleep-related symptoms, demography, and family and past medical history. Children screened due to high risk for OSA, along with a randomly chosen low-risk group, underwent overnight polysomnography (PSG).
Results:
A total of 6147 children (3032 girls) were studied. The overall prevalence of NE (≥1 wet night/month) was 4.6% (6.7% of boys and 2.5% of girls). Boys had a significantly greater prevalence across all age groups. In 597 children (215 girls) who underwent PSG, the prevalence of NE was not greater in children with OSA, but was increased with increasing severity of OSA in girls only. Boys with NE had longer deep sleep duration. Sex and sleep-related symptoms were associated with NE.
Conclusions:
This community-based study demonstrated a sex-associated prevalence of NE in relation to increasing OSA severity.
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