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Related Experiment Video

Updated: Jun 3, 2026

Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives

Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives

Published on: September 16, 2021

[Ovarian hyperstimulation syndrome].

A Le Gouez¹, B Naudin, M Grynberg

¹Département d'anesthésie-réanimation, hôpital Béclère, Assistance publique-Hôpitaux de Paris, Université Paris-Sud, 92141 Clamart, France. agnes.le-gouez@abc.aphp.fr

Annales Francaises D'Anesthesie Et De Reanimation

|March 15, 2011

Summary

This summary is machine-generated.

Ovarian hyperstimulation syndrome (OHSS) is a serious complication of assisted reproduction. Prevention through tailored ovarian stimulation protocols is the only effective treatment for this condition.

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A Method for Ovarian Follicle Encapsulation and Culture in a Proteolytically Degradable 3 Dimensional System

A Method for Ovarian Follicle Encapsulation and Culture in a Proteolytically Degradable 3 Dimensional System

Published on: March 15, 2011

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Last Updated: Jun 3, 2026

Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives

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Published on: September 16, 2021

A Method for Ovarian Follicle Encapsulation and Culture in a Proteolytically Degradable 3 Dimensional System

A Method for Ovarian Follicle Encapsulation and Culture in a Proteolytically Degradable 3 Dimensional System

Published on: March 15, 2011

Area of Science:

Reproductive Endocrinology
Obstetrics & Gynecology

Background:

Ovarian hyperstimulation syndrome (OHSS) is a significant complication of controlled ovarian hyperstimulation (COH) in assisted reproductive technologies.
The syndrome involves ovarian enlargement and fluid shifts, potentially leading to life-threatening circulatory issues.

Purpose of the Study:

To review the pathophysiology, clinical presentation, and management of OHSS.
To emphasize the critical role of prevention in managing OHSS.

Main Methods:

Review of existing literature on OHSS pathophysiology and clinical management.
Analysis of the role of vascular endothelial growth factor (VEGF) and gonadotropins in OHSS development.

Main Results:

OHSS is linked to increased capillary permeability, influenced by VEGF and cytokines released during COH.
Clinical manifestations range from mild ovarian enlargement to severe anasarca and circulatory dysfunction.
Thromboembolic complications contribute significantly to OHSS-related mortality.

Conclusions:

Effective OHSS management relies on preventing the syndrome by adjusting COH protocols based on individual risk factors.
There are no specific curative treatments for OHSS; management is primarily symptomatic.
Prevention is paramount due to the lack of specific treatments and the potential for severe, life-threatening complications.