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Related Experiment Video

Updated: Jun 3, 2026

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
04:30

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis

Published on: May 14, 2013

Carotid stenting: a surgeon's perspective.

Stephen K Allison1, Ilia Gur, William M Lee

  • 1Department of Surgery, University of Southern California, Keck School of Medicine, Pasadena, CA 91105, USA.

Journal of the American College of Surgeons
|March 15, 2011
PubMed
Summary
This summary is machine-generated.

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Carotid artery stenting (CAS) shows acceptable neurologic event rates in patients under 80. However, octogenarians face a disproportionately high stroke risk with CAS, suggesting surgery may be a safer option for this group.

Area of Science:

  • Vascular Surgery
  • Interventional Cardiology
  • Neurology

Background:

  • Recent studies show carotid stenting (CAS) outcomes comparable to endarterectomy.
  • Most trials were conducted in academic centers, necessitating evaluation in community settings.
  • This study assesses CAS outcomes performed by a single surgeon in a university-affiliated community hospital.

Purpose of the Study:

  • To evaluate the safety and efficacy of carotid artery stenting in a community hospital setting.
  • To compare outcomes of CAS in different age groups.
  • To determine if CAS results in community hospitals mirror those from academic centers.

Main Methods:

  • A retrospective review of 162 carotid artery stenting procedures in 149 patients over 5 years.

Related Experiment Videos

Last Updated: Jun 3, 2026

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
04:30

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis

Published on: May 14, 2013

  • Data collected included major/minor perioperative stroke, death, transient ischemic attack, myocardial infarction, restenosis, and late stroke.
  • A 2-tailed t-test was used for statistical comparison between patient groups.

    • Main Results:

    • 8 neurologic complications occurred in 162 stents (5%), including 3 transient ischemic attacks (1.85%), 3 minor strokes (1.85%), and 2 major strokes (1.23%).
    • Neurologic events and strokes were significantly higher in octogenarians (patients >80 years) compared to younger patients (p=0.0004 and p=0.0179).
    • One death within 30 days and no symptomatic myocardial infarctions were recorded.

    Conclusions:

    • Carotid artery stenting by a vascular surgeon yields acceptable neurologic event rates for patients under 80 years.
    • Octogenarians undergoing CAS exhibit a disproportionately high risk of stroke.
    • Surgical intervention may be a preferable treatment option for octogenarians with carotid stenosis.