Related Experiment Video
Updated: Jun 3, 2026

A Fast and Quantitative Method for Post-translational Modification and Variant Enabled Mapping of Peptides to Genomes
Published on: May 22, 2018
GeCo++: a C++ library for genomic features computation and annotation in the presence of variants
Matteo Cereda1, Manuela Sironi, Matteo Cavalleri
1Bioinformatics Lab, Scientific Institute I.R.C.C.S. E. Medea, Via Don L. Monza, Bosisio Parini (LC), Italy.
Unlabelled:
We propose a C++ class library developed to the purpose of making the implementation of sequence analysis algorithms easier and faster when genomic annotations and variations need to be considered. The library provides a class hierarchy to seamlessly bind together annotations of genomic elements to sequences and to algorithm results; it allows to evaluate the effect of mutations/variations in terms of both element position shifts and of algorithm results, limiting recalculation to the minimum. Particular care has been posed to keep memory and time overhead into acceptable limits.
Availability And Implementation:
A complete tutorial as well as a detailed doxygen generated documentation and source code is freely available at http://bioinformatics.emedea.it/geco, under the GPL license. The library was written in standard ISO C++, and does not depend on external libraries.
Related Concept Videos
Comparing Copy Number Variations and SNPs
Copy number variations or CNVs are the structural variations that cover more than 1kb of DNA sequence. The single nucleotide polymorphism (SNP), on the other hand, is a single nucleotide change or a point mutation that is found in more than 1%...
Genomics
Genome-wide Association Studies-GWAS
GWAS does not require the identification of the target gene involved in...
Genome Annotation and Assembly
Genetic Variation
Genes exist in different versions called alleles, which...
Single Nucleotide Polymorphisms-SNPs