Related Experiment Video
Updated: Jun 3, 2026

09:29
Investigating Drivers of Antireward in Addiction Behavior with Anatomically Specific Single-Cell Gene Expression Methods
Published on: August 4, 2022
Medication-assisted treatment for opioid dependence: making a difference in prisons
F1000 Medicine Reports
|March 15, 2011
Summary
This study reviews evidence for opioid maintenance therapies for incarcerated individuals. These treatments are increasingly supported for this population.
Area of Science:
- Addiction Medicine
- Public Health
- Criminal Justice Health
Background:
- Opioid use disorder (OUD) is prevalent in correctional facilities.
- Access to evidence-based treatment is often limited for incarcerated individuals.
- Continuity of care for OUD is a significant public health challenge.
Purpose of the Study:
- To examine the current evidence base for opioid maintenance therapies (OMT) in incarcerated populations.
- To assess the benefits and challenges of implementing OMT within correctional settings.
- To inform policy and practice regarding OUD treatment in prisons and jails.
Main Methods:
- Systematic review of existing literature.
- Analysis of studies on methadone, buprenorphine, and naltrexone in correctional settings.
- Evaluation of treatment outcomes, including retention, relapse, and overdose risk.
Main Results:
- Evidence supports the efficacy and safety of OMT for incarcerated individuals.
- OMT is associated with reduced illicit opioid use, disease transmission, and mortality post-release.
- Implementation challenges include medication access, staffing, and community reintegration.
Conclusions:
- Opioid maintenance therapies are a critical component of comprehensive OUD care for incarcerated populations.
- Expanding access to OMT in correctional facilities can improve individual and public health outcomes.
- Further research and policy development are needed to ensure effective implementation and continuity of care.
Related Concept Videos
Drug Therapy
The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Antianxiety Medications
Healthcare Agencies II
There are various healthcare agencies in the United States—some of which are managed by religious institutions and others by different government branches.
Parish nursing is a growing specialty nursing profession that focuses on holistic healthcare, health promotion, and illness prevention. It blends professional nursing practice with a health ministry, focusing on health and healing within the context of a Christian community. Parish nurses serve as health educators, referral sources, and lay...
Parish nursing is a growing specialty nursing profession that focuses on holistic healthcare, health promotion, and illness prevention. It blends professional nursing practice with a health ministry, focusing on health and healing within the context of a Christian community. Parish nurses serve as health educators, referral sources, and lay...
Opioid Analgesics: Synthetic and Semisynthetic Opioids
Synthetic and semisynthetic opioids are pivotal in pain management and tackling opioid addiction. Semisynthetic opioids, including morphinans (morphine derivatives), oxycodone, oxymorphone, hydrocodone, and hydromorphone, have improved pharmacokinetic profiles compared to morphine. Additionally, heroin and 6-MAM (6-Monoacetylmorphine) show better CNS penetration than morphine due to heightened lipid solubility. Hydromorphone, a potent opioid, undergoes hepatic metabolism to form the active...
Therapeutic Drug Monitoring: Affecting Factors
Therapeutic Drug Monitoring (TDM) is the clinical practice of measuring specific drug levels in a patient's blood or body tissues to manage and optimize therapy. TDM is crucial for drugs with narrow therapeutic windows, like warfarin and phenytoin, where incorrect doses can lead to treatment failure or severe side effects. This monitoring ensures the dosage administered is within a safe and effective range. The factors affecting therapeutic drug monitoring include:Patient-Specific Factors:a.
Drug Abuse and Addiction: Pharmacological Phenomena
Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not necessarily...
Pharmaceutical Poisoning: Treatment Strategies
Treatment strategies for poisoning are a critical aspect of emergency medicine, focusing on preventing the absorption of toxins and enhancing their elimination. When a poisoning incident occurs, the first response is to halt exposure and decontaminate the patient, particularly through gastrointestinal (GI) methods if the poison was ingested.Gastrointestinal Decontamination Techniques:Activated charcoal is the cornerstone of GI decontamination. It works through adsorption, binding the toxin to...

