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Related Concept Videos

Bone Disorders01:29

Bone Disorders

Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone Remodeling and Repair01:31

Bone Remodeling and Repair

Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during bone...
Bone Structure01:55

Bone Structure

Within the skeletal system, the structure of a bone, or osseous tissue, can be exemplified in a long bone, like the femur, where there are two types of osseous tissue: cortical and cancellous.
Essential Minerals for Bone Health01:31

Essential Minerals for Bone Health

The minerals contained in all of the food we consume are essential for our organ systems. However, certain essential minerals, such as calcium, phosphorus, magnesium, manganese, and fluoride, largely affect bone health.
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
Bone Remodeling01:40

Bone Remodeling

Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
Osteoclasts in Bone Remodeling01:31

Osteoclasts in Bone Remodeling

Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during bone...

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Related Experiment Video

Updated: Jun 3, 2026

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
07:56

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts

Published on: January 29, 2018

Bone quality: educational tools for patients, physicians, and educators.

Junaid Shams1, Allison B Spitzer, Ann M Kennelly

  • 1George Washington University School of Medicine, Children's National Medical Center, Washington, DC 20010, USA.

Clinical Orthopaedics and Related Research
|March 15, 2011
PubMed
Summary
This summary is machine-generated.

Identifying fracture risk is crucial for patient bone health. Tools like FRAX® and educational websites aid clinicians and patients in assessing and managing osteoporosis risk effectively.

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Trabecular Bone Microarchitecture Evaluation in an Osteoporosis Mouse Model
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Murine Hind Limb Long Bone Dissection and Bone Marrow Isolation
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Murine Hind Limb Long Bone Dissection and Bone Marrow Isolation

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Last Updated: Jun 3, 2026

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
07:56

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts

Published on: January 29, 2018

Trabecular Bone Microarchitecture Evaluation in an Osteoporosis Mouse Model
06:59

Trabecular Bone Microarchitecture Evaluation in an Osteoporosis Mouse Model

Published on: September 8, 2023

Murine Hind Limb Long Bone Dissection and Bone Marrow Isolation
07:17

Murine Hind Limb Long Bone Dissection and Bone Marrow Isolation

Published on: April 14, 2016

Area of Science:

  • Bone quality and fracture risk assessment.
  • Osteoporosis diagnosis and management.

Background:

  • Bone quality is difficult to define, but patient fracture likelihood is a key indicator.
  • Fracture risk indicators and performance measures aid in understanding individual risk.
  • Web-based educational resources improve communication and decision-making for patients and providers.

Purpose of the Study:

  • Identify tools for high fracture risk assessment.
  • Determine available clinical performance measures for bone health.
  • Outline strategies for identifying at-risk patients.
  • List authoritative web resources for bone quality education.

Main Methods:

  • Literature review using Google, PubMed, and trademark names with terms "bone quality" and "osteoporosis education."
  • Evaluation of web site legitimacy based on specific criteria.
  • Inclusion of English-language, nonprofit-sponsored educational websites.

Main Results:

  • Fracture Risk Assessment Tool (FRAX) and Fracture Risk Calculator (FRC) are reliable for assessing fracture risk.
  • Performance measures for bone health developed by AMA and Joint Commission.
  • Identification strategies include case finding, secondary cause evaluation, patient/provider education, and IT utilization.
  • Numerous authoritative educational websites are available for providers and patients.

Conclusions:

  • Effective clinical indicators, performance measures, and educational tools for fracture risk are available.
  • Broader adoption of these resources is needed for identification and therapy adherence in high-risk individuals.