Related Experiment Video

Updated: Jun 3, 2026

Herbal Munziq Ameliorates Myocardial Ischemia-Reperfusion Injury by Inhibiting Inflammation
09:53

Herbal Munziq Ameliorates Myocardial Ischemia-Reperfusion Injury by Inhibiting Inflammation

Published on: January 10, 2025

[Anesthetic maintenance during myocardial revascularization in patients over 70 years of age]

N A Trekova, B A Aksel'rod, M M Shmyrin

    Anesteziologiia I Reanimatologiia
    |March 15, 2011
    PubMed

    Insights

    Geriatric patients with coronary heart disease (CHD) face higher health risks. Optimized anesthesia management in elderly CHD patients can maintain hemodynamic stability, though careful monitoring for intraoperative complications is crucial.

    Area of Science:

    • Cardiology
    • Anesthesiology
    • Geriatrics

    Context:

    • Coronary heart disease (CHD) poses unique challenges in elderly patients.
    • Geriatric patients (70-83 years) exhibit higher comorbidities compared to younger adults (40-59 years).
    • Comorbidities include arterial hypertension, respiratory and CNS diseases, arrhythmias, and anemia.

    Purpose:

    • To compare preoperative and intraoperative periods in elderly CHD patients versus a younger control group.
    • To evaluate the efficacy of a specific balanced general anesthesia protocol in elderly CHD patients.

    Summary:

    • Elderly CHD patients demonstrated increased incidence of comorbidities.
    • A balanced anesthesia protocol (low-dose midazolam, fentanyl, sub-anesthetic ketamine, isoflurane, infusion therapy) achieved hemodynamic stability during induction and preperfusion.
    • Intraoperatively, elderly patients experienced greater reductions in oxygenation and body temperature, requiring more cardiotonic, diuretic, and erythrocyte mass support.

    Impact:

    • Suggests a tailored anesthetic approach can mitigate risks in elderly CHD patients.
    • Highlights the need for vigilant intraoperative monitoring and management of physiological changes in this population.
    • Provides insights into optimizing anesthetic care for geriatric cardiac surgery patients.

    More Related Videos

    Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery09:12

    Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery

    Published on: March 27, 2018

    Related Concept Videos

    Cardiomyopathy VII: Pre and Post Operative Nursing Management01:28

    Cardiomyopathy VII: Pre and Post Operative Nursing Management

    Patients with hypertrophic cardiomyopathy (HCM) and left ventricular outflow tract (LVOT) obstruction who remain symptomatic despite optimal medical therapy may undergo a septal myectomy (Morrow procedure). This procedure involves excising a portion of the hypertrophied septum below the aortic valve using a heart-lung machine to improve blood flow through the LVOT. Effective preoperative and postoperative nursing management ensures successful patient outcomes, minimizes complications, and...
    Aneurysm IV: Nursing Management01:22

    Aneurysm IV: Nursing Management

    Vigilant monitoring for aneurysm rupture is essential for patients undergoing aortic surgery.Preoperative Nursing ManagementContinuously monitor the patient for manifestations of aneurysm rupture, such as pallor, weakness, tachycardia, hypotension, abdominal, back, groin, or periumbilical pain, changes in consciousness, and a pulsating abdominal mass. Regularly assess the patient's peripheral pulses.Instruct the patient to consume a clear liquid diet the day before surgery and administer...
    Cardiopulmonary Resuscitation IV: Pharmacological Management01:25

    Cardiopulmonary Resuscitation IV: Pharmacological Management

    Pharmacologic intervention is crucial in treating cardiac arrest patients during ACLS or Advanced Cardiovascular Life Support. The ACLS algorithms guide the administration of specific drugs based on the patient's cardiac arrest rhythm, which includes pulseless ventricular tachycardia (VT), ventricular fibrillation (VF), asystole, and pulseless electrical activity (PEA).EpinephrineIndication: Epinephrine is the first-line drug for all cardiac arrest rhythms.Mechanism of Action: Epinephrine...
    General Anesthesia: Overview01:24

    General Anesthesia: Overview

    Anesthesia is a medical procedure that uses drugs for CNS suppression to enable painless surgeries and procedures. The selection of anesthetics is influenced by their pharmacokinetic properties, side effects, and patient characteristics. Various types of anesthesia include general, local, regional, spinal, and inhalational.
    General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
    Pharmacodynamics in Geriatric Patients: Effects of Age01:27

    Pharmacodynamics in Geriatric Patients: Effects of Age

    Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
    Angina IV: Management01:26

    Angina IV: Management

    IntroductionThe management of angina requires a comprehensive approach that includes pharmacological therapies, medical procedures, and lifestyle modifications.Pharmacological TherapiesAntiplatelet agents, such as aspirin, clopidogrel, prasugrel, and ticagrelor, play a pivotal role in preventing thrombus formation in patients with angina. These medications inhibit platelet aggregation and reduce the likelihood of myocardial infarction and other cardiovascular events.Anticoagulants, including...