Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Arboviral Encephalitis01:25

Arboviral Encephalitis

Arboviral encephalitis refers to brain inflammation caused by arthropod-borne viruses, particularly those transmitted through mosquito vectors. Among these, West Nile virus (WNV), a member of the Flaviviridae family, is a significant public health concern. WNV is an enveloped, positive-sense, single-stranded RNA virus. Human infection typically begins when an infected mosquito introduces the virus into the dermis during feeding. The primary transmission cycle involves birds as amplifying hosts...
Encephalitis ll: Pathophysiology01:26

Encephalitis ll: Pathophysiology

Encephalitis is inflammation of the brain parenchyma caused by direct viral invasion or immune-mediated mechanisms triggered by infections or tumors. Both processes lead to neuronal injury, disrupted neurotransmission, and diverse neurological symptoms, often with overlapping clinical and pathological features.Autoimmune EncephalitisIn autoimmune encephalitis, antibodies target neuronal antigens on cell surfaces, synapses, or within neurons. A key example is anti-NMDAR encephalitis, which can...
Rabies01:28

Rabies

Rabies is a lethal zoonotic disease caused by a single-stranded, negative-sense RNA virus of the Lyssavirus genus, within the family Rhabdoviridae. Its primary mode of transmission to humans is through bites or saliva-contaminated scratches from infected mammals such as dogs, bats, raccoons, or foxes. Transmission can also occur if infectious saliva contacts abraded skin or intact mucous membranes, including the conjunctiva.Viral Entry and Early ReplicationOnce introduced at the bite or scratch...
Encephalitis l: Introduction01:19

Encephalitis l: Introduction

Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...
Hepatic Encephalopathy01:29

Hepatic Encephalopathy

DefinitionHepatic encephalopathy is a reversible neurologic syndrome that results from advanced liver dysfunction or portosystemic shunting. It leads to disturbances in cognition, behavior, and motor function due to the brain’s exposure to gut-derived toxins that the liver fails to detoxify.EtiologyThis condition develops either in the setting of acute fulminant hepatitis or progressively during chronic liver disease, such as cirrhosis and portal hypertension. Portosystemic shunting—including...
Viral Meningitis01:18

Viral Meningitis

Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Case of Autosomal Dominant Alport Syndrome Diagnosed Just Before Discontinuation of Follow-Up.

Pediatric reports·2026
Same author

Delayed Peri-Implant Trochanteric Femoral Fractures After Intramedullary Nailing: Surgical Challenges in an Aging Society: A Two-Case Report.

Case reports in orthopedics·2026
Same author

Development of a zebrafish model of Loeys-Dietz syndrome through tgfbr2b knockdown.

Journal of human genetics·2026
Same author

Non-invasive biomarkers in pediatric MASLD: utility of gamma-glutamyltransferase for steatohepatitis and the FIB-4 index for fibrosis.

BMC pediatrics·2025
Same author

Hemodynamic and cerebral oxygenation predictors of visual darkening in pediatric POTS: a cross-sectional study.

Clinical autonomic research : official journal of the Clinical Autonomic Research Society·2025
Same author

High-intensity focused ultrasound rectoanal lifting (HIFU-RAL) for prolapsed hemorrhoids: a case series.

Journal of surgical case reports·2025

Related Experiment Video

Updated: Jun 3, 2026

Oral Administration of Rotenone using a Gavage and Image Analysis of Alpha-synuclein Inclusions in the Enteric Nervous System
11:53

Oral Administration of Rotenone using a Gavage and Image Analysis of Alpha-synuclein Inclusions in the Enteric Nervous System

Published on: October 26, 2010

[Rota virus encephalopathy].

Yasuyo Kashiwagi1, Hisashi Kawashima, Shunsuke Suzuki

  • 1Department of Pediatrics, Tokyo Medical University.

Nihon Rinsho. Japanese Journal of Clinical Medicine
|March 16, 2011
PubMed
Summary

Rotavirus gastroenteritis can affect the central nervous system (CNS), leading to encephalopathy and other severe outcomes in children. This review covers recent advances in understanding rotavirus encephalopathy, including its causes, prognosis, and treatments.

Area of Science:

  • Virology
  • Pediatric Neurology
  • Infectious Diseases

Context:

  • Rotavirus is a leading cause of severe gastroenteritis in young children globally.
  • The central nervous system (CNS) complications of rotavirus infection, known as rotavirus encephalopathy, are less understood.
  • Rotavirus encephalopathy is associated with significant morbidity and mortality, including seizures, encephalopathy, and death.

Purpose:

  • To review recent advances in the understanding of rotavirus encephalopathy.
  • To consolidate information on the causative agent, pathogenesis, clinical features, prognosis, and treatment of rotavirus-induced CNS involvement.
  • To highlight the clinical significance of rotavirus encephalopathy in pediatric populations.

Summary:

  • Rotavirus, a common cause of childhood gastroenteritis, can also lead to central nervous system (CNS) involvement.

More Related Videos

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
04:23

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease

Published on: April 28, 2019

The Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy (rNAION)
06:49

The Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy (rNAION)

Published on: November 20, 2016

Related Experiment Videos

Last Updated: Jun 3, 2026

Oral Administration of Rotenone using a Gavage and Image Analysis of Alpha-synuclein Inclusions in the Enteric Nervous System
11:53

Oral Administration of Rotenone using a Gavage and Image Analysis of Alpha-synuclein Inclusions in the Enteric Nervous System

Published on: October 26, 2010

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
04:23

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease

Published on: April 28, 2019

The Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy (rNAION)
06:49

The Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy (rNAION)

Published on: November 20, 2016

  • Rotavirus encephalopathy presents with clinical signs of encephalopathy, potentially with cerebrospinal fluid (CSF) abnormalities.
  • This review synthesizes current knowledge on rotavirus encephalopathy's etiology, disease mechanisms, clinical course, and therapeutic strategies.

    • Impact:

    • Enhances understanding of a severe, under-recognized complication of rotavirus infection.
    • Provides a comprehensive overview for clinicians and researchers managing pediatric CNS infections.
    • Highlights the need for further research into the pathogenesis and treatment of rotavirus encephalopathy.