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[Early ultrasonic amniocentesis. 147 cases].
G Darconza1, S Paradiso, R Trentadue
1Divisione Ostetricia-Ginecologia, IRCCS, Castellana Grotte, Bari.
Minerva Ginecologica
|March 1, 1990
Summary
Amniocentesis successfully identified chromosome abnormalities in 1.4% of cases, including two instances of Down syndrome. This prenatal diagnostic procedure showed no adverse materno-foetal complications.
Area of Science:
- Obstetrics and Gynecology
- Medical Genetics
- Prenatal Diagnosis
Context:
- Amniocentesis is a common prenatal diagnostic procedure.
- Evaluating the safety and efficacy of amniocentesis is crucial for maternal and fetal health.
- Chromosome abnormalities are a significant concern in pregnancy.
Purpose:
- To analyze the outcomes of 147 amniocentesis procedures.
- To determine the incidence of chromosome abnormalities detected via amniocentesis.
- To assess the occurrence of materno-foetal complications following amniocentesis.
Summary:
- Analysis of 147 amniocenteses revealed a 1.4% rate of chromosome abnormalities.
- Two cases of Down syndrome (trisomy 21) were diagnosed.
- No short-term or long-term materno-foetal complications were observed post-procedure.
Impact:
- Highlights the diagnostic value of amniocentesis in detecting fetal genetic disorders.
- Demonstrates the safety profile of amniocentesis, with no reported complications.
- Provides data supporting the continued use of amniocentesis in prenatal care for genetic screening.