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Related Experiment Video

Updated: Jun 3, 2026

Quantitative Examination of Antibiotic Susceptibility of Neisseria gonorrhoeae Aggregates Using ATP-utilization Commercial Assays and Live/Dead Staining

Quantitative Examination of Antibiotic Susceptibility of Neisseria gonorrhoeae Aggregates Using ATP-utilization Commercial Assays and Live/Dead Staining

Published on: February 8, 2019

Gonorrhoea.

Sarah Creighton¹

¹Department of Sexual Health, Homerton University Hospital, London, UK.

BMJ Clinical Evidence

|March 16, 2011

Summary

This summary is machine-generated.

This systematic review examines antibiotic treatments for gonorrhoea, including co-infections with chlamydia. It assesses effectiveness and safety, crucial for combating rising antimicrobial resistance.

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Fluorescence Microscopy Methods for Determining the Viability of Bacteria in Association with Mammalian Cells

Fluorescence Microscopy Methods for Determining the Viability of Bacteria in Association with Mammalian Cells

Published on: September 5, 2013

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Last Updated: Jun 3, 2026

Quantitative Examination of Antibiotic Susceptibility of Neisseria gonorrhoeae Aggregates Using ATP-utilization Commercial Assays and Live/Dead Staining

Quantitative Examination of Antibiotic Susceptibility of Neisseria gonorrhoeae Aggregates Using ATP-utilization Commercial Assays and Live/Dead Staining

Published on: February 8, 2019

Fluorescence Microscopy Methods for Determining the Viability of Bacteria in Association with Mammalian Cells

Fluorescence Microscopy Methods for Determining the Viability of Bacteria in Association with Mammalian Cells

Published on: September 5, 2013

Area of Science:

Infectious Diseases
Microbiology
Public Health

Background:

High gonorrhoea diagnosis rates in young adults in the UK.
Over 25% of gonorrhoea isolates show antimicrobial resistance.
Co-infection with Chlamydia trachomatis is common (10-40%).

Purpose of the Study:

To evaluate treatments for uncomplicated gonorrhoea in men and women.
To assess treatments for disseminated gonococcal infection.
To determine the effectiveness of dual treatment for gonorrhoea and chlamydia.

Main Methods:

Systematic review of 24 studies (reviews, RCTs, observational studies).
Searched major databases (Medline, Embase, Cochrane Library) up to March 2010.
Included safety alerts from FDA and MHRA.

Main Results:

Evaluated antibiotic regimens including dual treatment, multiple, and single doses.
Assessed interventions for uncomplicated and disseminated gonococcal infections.
Utilized GRADE methodology to evaluate evidence quality.

Conclusions:

Presents findings on the effectiveness and safety of various antibiotic regimens.
Provides evidence-based information for gonorrhoea treatment strategies.
Highlights the importance of considering co-infections and resistance patterns.