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Does an intervention that improves infant sleep also improve overweight at age 6? Follow-up of a randomised trial
Melissa Wake1, Anna Price, Susan Clifford
1Centre for Community Child Health, Royal Children's Hospital, Flemington Road, Parkville, VIC 3052, Australia. melissa.wake@rch.org.au
Insights
A brief infant sleep intervention did not reduce childhood obesity by age 6. This study suggests that population-based sleep services may not effectively combat the early childhood obesity epidemic.
Area of Science:
- Pediatrics
- Public Health
- Sleep Medicine
Background:
- Short sleep duration is linked to childhood obesity.
- Sleep interventions offer a potential prevention strategy.
- Infant sleep problems are common and may influence long-term health.
Purpose of the Study:
- To evaluate the impact of a behavioral infant sleep intervention on childhood adiposity.
- To determine if reducing parent-reported infant sleep problems affects body mass index (BMI) and obesity at age 6.
- To explore the association between sleep duration and anthropometric outcomes in children.
Main Methods:
- A 5-year follow-up of a population-based cluster randomized trial.
- 328 infants with sleep problems received either a behavioral sleep intervention or usual care.
- Outcomes measured at age 6 included BMI z-score, overweight/obesity status, and waist circumference, analyzed via intention-to-treat.
Main Results:
- No significant difference in BMI z-score, overweight/obesity prevalence, or waist circumference was observed between intervention and control groups at age 6.
- Retention rate was 59% with anthropometric data available for 193 children.
- Posthoc analyses found no association between infant or childhood sleep duration and anthropometric outcomes.
Conclusions:
- A brief behavioral intervention for infant sleep problems did not reduce overweight or obesity at age 6.
- Population-based primary care sleep services are unlikely to be effective in reducing the childhood obesity epidemic.
- Further research may be needed to identify effective strategies for obesity prevention through sleep interventions.
Objective:
Short sleep duration may contribute to childhood obesity. Amenable to intervention, sleep thus provides a potential path for prevention. The authors aimed to determine the impact of a behavioural intervention that successfully reduced parent-reported infant sleep problems on adiposity at age 6.
Design:
5-year follow-up of a previously reported population-based cluster randomised trial. Participant allocation was concealed to researchers and data collection blinded.
Setting:
Recruitment from well-child centres in Melbourne, Australia.
Participants:
328 children (174 intervention) with parent-reported sleep problems at age 7-8 months drawn from 49 centres (clusters).
Intervention:
Behavioural sleep strategies delivered over one to three structured individual nurse consultations from 8 to 10 months, versus usual care. MAIN OUTCOMES AT AGE 6 YEARS: Body mass index (BMI) z-score, percentage overweight/obese and waist circumference.
Analyses:
Intention-to-treat regression analyses adjusted for potential confounders.
Results:
Anthropometric data were available for 193 children (59% retention) at age 6. There was no evidence of a difference between intervention (N=101) and control (N=92) children for BMI z-score (adjusted mean difference 0.2, 95% CI -0.1 to 0.4), overweight/obese status (20% vs 17%; adjusted OR 1.4, 95% CI 0.7 to 2.8) and waist circumference (adjusted mean difference -0.3, 95% CI -1.6 to 1.1). In posthoc analyses, neither infant nor childhood sleep duration were associated with anthropometric outcomes.
Conclusions:
A brief infant sleep intervention did not reduce overweight/obesity at 6 years. Population-based primary care sleep services seem unlikely to reduce the early childhood obesity epidemic.
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