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Related Concept Videos

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...

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Related Experiment Video

Updated: Jun 3, 2026

A Neonatal Mouse Spinal Cord Compression Injury Model
13:31

A Neonatal Mouse Spinal Cord Compression Injury Model

Published on: March 27, 2016

Pediatric sciatic neuropathies: a 30-year prospective study.

J Srinivasan1, M M Ryan, D M Escolar

  • 1Department of Neurology, Lahey Clinic, 41 Mall Road, Burlington, MA 01805, USA. jayashri_srinivasan@lahey.org

Neurology
|March 16, 2011
PubMed
Summary
This summary is machine-generated.

Sciatic neuropathy (SN) in children is uncommon and has varied causes like trauma and surgery. Recovery depends on the injury

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Reproducible Mouse Sciatic Nerve Crush and Subsequent Assessment of Regeneration by Whole Mount Muscle Analysis
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Published on: February 22, 2012

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Last Updated: Jun 3, 2026

A Neonatal Mouse Spinal Cord Compression Injury Model
13:31

A Neonatal Mouse Spinal Cord Compression Injury Model

Published on: March 27, 2016

Reproducible Mouse Sciatic Nerve Crush and Subsequent Assessment of Regeneration by Whole Mount Muscle Analysis
08:49

Reproducible Mouse Sciatic Nerve Crush and Subsequent Assessment of Regeneration by Whole Mount Muscle Analysis

Published on: February 22, 2012

Area of Science:

  • Pediatric Neurology
  • Nerve Injury
  • Electrophysiology

Background:

  • Sciatic neuropathy (SN) in children is poorly understood.
  • This study reviews 30 years of pediatric SN cases.

Purpose of the Study:

  • To understand the incidence, causes, and prognosis of pediatric sciatic neuropathy.
  • To analyze electrophysiologic findings in children with SN.

Main Methods:

  • Prospective review of 53 pediatric patients with sciatic neuropathy.
  • Analysis of patient history, physical exams, electrophysiologic studies, and clinical course.

Main Results:

  • Varied etiologies include trauma, iatrogenic causes, tumors, and vascular issues.
  • Electrophysiologic studies showed high rates of abnormalities in motor and sensory nerves.
  • Needle EMG was abnormal in all subjects for peroneal-innervated muscles.

Conclusions:

  • Pediatric sciatic neuropathy is an uncommon mononeuropathy with diverse causes.
  • Electrophysiologic studies are crucial for diagnosis in children, despite potential tolerance issues.
  • Prognosis varies based on etiology and injury severity.