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Priapism in hematological and coagulative disorders: an update
Belinda F Morrison1, Arthur L Burnett
1Division of Urology, Department of Surgery, University of the West Indies, Mona, Mona P.O., Kingston 7, Jamaica.
Nature Reviews. Urology
|March 16, 2011
Summary
Priapism, a painful erection, is a urological emergency. This review focuses on priapism in patients with hematological disorders, emphasizing urgent diagnosis, treatment, and prophylaxis strategies.
Area of Science:
- Urology
- Hematology
Background:
- Priapism is a medical emergency characterized by persistent, painful erections.
- Patients with hematological disorders (e.g., sickle cell disease) are at high risk.
- Delayed treatment can lead to irreversible erectile dysfunction.
Purpose of the Study:
- To review priapism in the context of hematological disorders.
- To highlight diagnostic and emergency treatment protocols.
- To discuss emerging prophylactic measures for high-risk patients.
Main Methods:
- Review of current literature on priapism and hematological disorders.
- Analysis of diagnostic criteria including patient history, physical examination, and corporal blood gas analysis.
- Evaluation of established and novel treatment and prophylaxis strategies.
Main Results:
- Urgent diagnosis is critical for successful management of priapism.
- Prompt intervention is necessary to prevent long-term complications like erectile dysfunction.
- Prophylaxis is crucial for high-risk patient groups, with new strategies under development.
Conclusions:
- Priapism requires immediate urological intervention.
- Understanding the pathophysiology in hematological disorders informs better prophylaxis.
- A multidisciplinary approach is key for managing priapism in at-risk populations.
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