Related Experiment Video
Updated: Jun 3, 2026

Developing a Rat Model for Bipolar Disorder
Published on: May 2, 2025
Chronic unipolar mania. A case report
Alvaro Frías-Ibáñez1, Beatriz García-Carrera, Noelia Cervera-Elegido
1Unidad de Larga Estancia de Bétera Valencia. alvarofrias66@hotmail.com
Introduction:
Bipolar disorder is a phasic mental disorder characterized by the presence of (hypo) maniac, depressive and/or mixed episodes during the course of the disease.
Clinical Case:
A middle-age man, with no prior history of depressive episodes, began to suffer a picture of manic characteristics as an adolescent that has lasted for 18 years. Despite the numerous drug treatments prescribed, there has been no improvement, and the disorder has followed a torpid and chronic course.
Conclusions:
Chronic unipolar mania is a clinical entity appearing as a residual characteristic in the current psychiatric nosology. Its low prevalence makes it difficult to carry out research aimed at elucidating whether it has a subordinate or independent relationship with the bipolar disorder. A systematic assessment of the effectiveness of electroconvulsive therapy is needed in these patients.
Related Concept Videos
Bipolar Disorder
Mania and Antimanic Drugs: Overview
Methods of Documentation VI: Case Management Model
For example, a patient with a chronic illness...
Panic Disorder
Depressive Disorders: MDD and Dysthymia
Psychosis: Goals of Pharmacotherapy