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Related Experiment Video

Updated: Jun 3, 2026

Measuring Naturally Acquired Phagocytosis-Inducing Antibodies to Plasmodium falciparum Parasites by a Flow Cytometry-Based Assay

Measuring Naturally Acquired Phagocytosis-Inducing Antibodies to Plasmodium falciparum Parasites by a Flow Cytometry-Based Assay

Published on: August 6, 2020

Malaria in pregnancy.

Subrata Lall Seal¹, Sima Mukhopadhay, Rajendra Prasad Ganguly

¹Department of Obstetrics and Gynaecology, RG Kar Medical College, Kolkata 700004.

Journal of the Indian Medical Association

|March 17, 2011

Summary

Malaria in pregnancy significantly increases risks for mothers and babies, leading to severe complications like anemia and preterm labor. Prevention is crucial due to high maternal mortality and adverse neonatal outcomes.

Area of Science:

Obstetrics and Gynecology
Infectious Diseases
Maternal-Fetal Medicine

Background:

Malaria during pregnancy poses significant risks for both mother and fetus.
Pregnancy can exacerbate malaria severity, particularly with Plasmodium falciparum infections.

Purpose of the Study:

To investigate the maternal and fetal outcomes of malaria in pregnant women.
To compare complications in pregnant women with malaria against non-pregnant controls.

Main Methods:

Prospective observational study from January 2001 to December 2006.
Involved 40 pregnant women with malaria and 40 non-pregnant controls.
Compared maternal complications and pregnancy outcomes between groups.

Main Results:

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In Vivo Tracking of Edema Development and Microvascular Pathology in a Model of Experimental Cerebral Malaria Using Magnetic Resonance Imaging

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Pregnant women with malaria showed significantly higher rates of anemia, cerebral malaria, renal/hepatic failure, hypotension, and death (p < 0.05).
Increased incidence of abortion, preterm labor, intrauterine growth restriction, and fetal death observed.
Plasmodium falciparum infection was more prevalent during pregnancy.

Conclusions:

Malaria in pregnancy is associated with substantial maternal morbidity and mortality.
Adverse neonatal outcomes are linked to malaria during gestation.
Preventive measures against malaria in pregnancy are essential.