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Updated: Jun 3, 2026

Assembling Molecular Shuttles Powered by Reversibly Attached Kinesins
Published on: January 26, 2019
Motion reversal of molecular motor assemblies due to weak noise
T Guérin1, J Prost, J-F Joanny
1Physicochimie Curie, Institut Curie/CNRS-UMR168/UPMC, Institut Curie, Centre de Recherche, 26 rue d'Ulm 75248 Paris Cedex 05 France.
Abstract:
Bidirectional motion is an example of collective behavior of molecular motors. It occurs at finite noise level in a nonequilibrium system. We consider this problem as a first exit problem. We identify the noise strength by doing an expansion of a master equation and apply the Wentzell-Freidlin theory to define an effective nonequilibrium potential and provide analytical estimates of the reversal time. Our results match very well with the results of stochastic simulations.
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