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Updated: Jun 3, 2026

High-Resolution Neutron Spectroscopy to Study Picosecond-Nanosecond Dynamics of Proteins and Hydration Water
Published on: April 28, 2022
Proteins as fractals: role of the hydrodynamic interaction
1Stella and Avram Goren-Goldstein Department of Biotechnology Engineering and Ilse Katz Institute for Meso and Nanoscale Science and Technology, Ben-Gurion University of The Negev, Beer Sheva 84105, Israel.
Abstract:
Exploiting the fractal nature of folded proteins, we study the effect of the hydrodynamic interaction between amino acids using a Zimm-type model. We compute the time-dependent mean square displacement of an amino acid and the time-dependent autocorrelation function of the distance between two amino acids, and we show that these dynamic quantities evolve anomalously, similar to the Rouse-type behavior, yet with modified dynamic exponents. Good agreement is found with recent neutron spin-echo studies of myoglobin and hemoglobin.
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