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Updated: Jun 3, 2026

HPLC-based Assay to Monitor Extracellular Nucleotide/Nucleoside Metabolism in Human Chronic Lymphocytic Leukemia Cells
Published on: July 20, 2016
Reverse pseudohyperkalemia in heparin plasma samples from a patient with chronic lymphocytic leukemia
1Department of Pathology and Laboratory Medicine, Royal University Hospital, University of Saskatchewan, Saskatoon, Saskatchewan, Canada. qing.meng@usask.ca
Objectives:
To investigate the spurious high potassium results in heparin plasma.
Design And Methods:
Potassium values from heparin plasma, serum, and whole blood in a patient with chronic lymphocytic leukemia were determined and compared on chemistry and blood gas analyzers.
Results:
Potassium levels were strikingly elevated in heparin plasma compared to serum or whole blood in which the potassium levels were surprisingly normal.
Conclusions:
The phenomenon of reverse pseudohyperkalemia should be publicized.
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