Related Experiment Video
Updated: Jun 3, 2026

Developing a Rat Model for Bipolar Disorder
Published on: May 2, 2025
Childhood leukodystrophy presenting as secondary bipolar disorder
H S Duggal1, V K Sinha, S H Nizamie
1HARPREET S.DUGGAL, DPM., Resident, Central Institute of Psychiatry, Kanke, Ranchi 834 006.
Abstract:
Leukodystrophies are rare dysmyelinating disorders of the nervous system, which occasionally have an initial psychiatric presentation. This report describes a case of a 9-year-old boy whose initial presentation resembled a bipolar disorder but subsequent work-up revealed an underlying leukodystrophy, most likely Alexander's disease. The course of this rare disease along with the implications of making a diagnosis of leukodystrophy in a psychiatric setting is discussed.
Related Concept Videos
Bipolar Disorder
Mania and Antimanic Drugs: Overview
Borderline Personality Disorder
Genetic and Environmental Contributions
Borderline Personality...
Oppositional Defiant Disorder
Diagnostic Criteria and...
Conduct Disorder
Epilepsy ll: Types