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Related Experiment Video

Updated: Jun 3, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

Adverse events after zolpidem intake.

R Thara¹

¹Director, Schizophrenia Research Foundation(SARF), Plot No. R/7A, North Main Road, Anna Nagar (west extn), Chennai-600 101 scarf@vsnl.com.

Indian Journal of Psychiatry

|March 17, 2011

Summary

Adverse reactions to Zolpidem, a common sleep aid, were reported in two cases. Both incidents involved a 10mg dose, with reactions occurring approximately 15 minutes after ingestion.

Area of Science:

Pharmacology
Clinical Toxicology
Neuroscience

Background:

Zolpidem is a widely prescribed sedative-hypnotic medication used for insomnia.
Adverse drug reactions (ADRs) can impact patient safety and treatment efficacy.
Understanding the specific ADRs associated with Zolpidem is crucial for clinical practice.

Purpose of the Study:

To report and analyze two distinct cases of adverse reactions to Zolpidem.
To highlight the temporal relationship between Zolpidem intake and the onset of adverse events.
To contribute to the pharmacovigilance data on Zolpidem.

Main Methods:

Case report methodology was employed.
Detailed clinical histories of two patients experiencing adverse reactions to Zolpidem were reviewed.

Keywords:

Zolpidem adverse effects

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The timing and dosage of Zolpidem administration were documented.

Main Results:

Two separate cases of adverse reactions to Zolpidem were identified.
In both instances, the adverse reaction occurred following a 10mg dosage of Zolpidem.
The onset of the adverse reactions was consistently observed around 15 minutes post-ingestion.

Conclusions:

Zolpidem, even at a standard 10mg dose, can precipitate adverse reactions in susceptible individuals.
The rapid onset of reactions (approx. 15 minutes) suggests a swift pharmacokinetic or pharmacodynamic effect.
These case reports underscore the importance of monitoring patients for immediate adverse effects after Zolpidem administration.