Related Experiment Videos
Venlafaxine induced hypertension:a case report
P K Pardal1, T R John, S P Rathee
1LT. COL. P.K. PARDAL, MD., Psychiatrist, Department of Psychiatry, Command Hospital (WC), Chandimandir-134107.
Indian Journal of Psychiatry
|March 17, 2011
Summary
Venlafaxine, a new antidepressant, may cause severe hypertension. This case report emphasizes the need for careful monitoring and cautious use of this medication.
Area of Science:
- Pharmacology
- Clinical Medicine
- Neuroscience
Background:
- Venlafaxine is a novel antidepressant with distinct clinical properties.
- It exhibits a unique mechanism of action compared to other antidepressants.
- Potential for unique efficacy and rapid onset of action has been suggested.
Purpose of the Study:
- To report a case of severe hypertension induced by venlafaxine.
- To underscore the importance of caution when prescribing venlafaxine.
- To contribute to understanding the adverse effect profile of venlafaxine.
Main Methods:
- Case report.
- Clinical observation and patient monitoring.
- Review of venlafaxine's pharmacological profile.
Main Results:
- A patient developed severe hypertension during venlafaxine treatment.
- The hypertension was attributed to venlafaxine administration.
- This adverse event highlights a potential risk associated with the drug.
Conclusions:
- Venlafaxine can induce severe hypertension.
- Healthcare providers should exercise caution when prescribing venlafaxine.
- Close monitoring for blood pressure changes is recommended for patients on venlafaxine.
Related Concept Videos
01:30Hypertension III: Clinical Manifestations and Diagnostic Studies
Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
01:23Antidepressant Drugs: MAOIs and Other Agents
Atypical antidepressants, including bupropion (Wellbutrin), mirtazapine (Remeron), nefazodone (Serzone), trazodone (Desyrel), and vilazodone (Viibryd), offer unique mechanisms of action. Bupropion weakly inhibits dopamine and norepinephrine reuptake, aiding depression treatment and smoking cessation, with a low risk of sexual dysfunction. Mirtazapine enhances serotonin and norepinephrine neurotransmission, leading to sedation, increased appetite, and weight gain. As a result, it helps treat...
01:28Hypertension I: Introduction
Hypertension is a widespread, long-term medical condition where blood pressure in the arteries remains elevated. It is characterized by systolic blood pressure readings of 130 mm Hg or above or diastolic blood pressure (DBP) readings of 80 mm Hg or higher. Unmanaged hypertension poses significant health risks, making the distinction between primary (or essential) hypertension and secondary hypertension crucial, as their management and implications vary.Primary HypertensionPrimary hypertension,...
01:23Hypertension V: Nursing Management
The nursing management of hypertension involves accurately assessing symptoms, making a comprehensive nursing diagnosis, collaborating with patients to set goals, and implementing targeted interventions to mitigate the condition's impact and improve patient well-being.Comprehensive AssessmentThe initial step in nursing care for hypertension involves a thorough patient assessment. It includes evaluating symptoms such as headaches, dizziness, blurred vision, and previous hypertension episodes.
01:29Hypertension II: Pathophysiology
Hypertension is a chronic condition in which the blood's force against artery walls is excessively high, posing risks such as heart disease. The condition's underlying mechanisms involve complex interactions among the cardiovascular, kidney, and autonomic nervous systems.Renin-Angiotensin-Aldosterone System (RAAS): This system significantly influences blood pressure regulation. When blood pressure decreases, the kidneys secrete renin. This enzyme transforms angiotensinogen, a plasma protein,...
01:28Hypertension IV: Drug Therapy and Lifestyle Modifications
Multiple classes of antihypertensive medications are employed in treating hypertension. The most commonly recommended first-line treatments include:Thiazide Diuretics, such as chlorthalidone, increase sodium and water excretion from the body, reducing blood volume and blood pressure.Angiotensin-converting enzyme inhibitors, like lisinopril, block the conversion of angiotensin I to II, a potent vasoconstrictor lowering blood pressure.Angiotensin II Receptor Blockers (ARBs) prevent angiotensin II...