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Related Experiment Video

Updated: Jun 3, 2026

Thermostabilization, Expression, Purification, and Crystallization of the Human Serotonin Transporter Bound to S-citalopram

Thermostabilization, Expression, Purification, and Crystallization of the Human Serotonin Transporter Bound to S-citalopram

Published on: November 27, 2016

Sertraline induced hypomania.

R Kumar¹, C K Dubey, V K Sinha

¹RATANENDRA KUMAR, B.Sc., MBBS., DPM., Resident, Central Institute of Psychiatry.

Indian Journal of Psychiatry

|March 17, 2011

Summary

This summary is machine-generated.

Selective serotonin reuptake inhibitors (SSRIs) are less commonly linked to mania than tricyclic antidepressants. This case study details a rare instance of sertraline-induced mania in an adolescent female.

Keywords:

Sertraline adolescent female mania

Related Experiment Videos

Last Updated: Jun 3, 2026

Thermostabilization, Expression, Purification, and Crystallization of the Human Serotonin Transporter Bound to S-citalopram

Thermostabilization, Expression, Purification, and Crystallization of the Human Serotonin Transporter Bound to S-citalopram

Published on: November 27, 2016

Area of Science:

Psychiatry
Pharmacology
Neuroscience

Background:

Tricyclic antidepressants are known to induce mania.
Reports of mania induced by selective serotonin reuptuptake inhibitors (SSRIs) are less frequent in medical literature.

Purpose of the Study:

To report a case of mania induced by sertraline, a commonly prescribed SSRI.
To discuss the implications of sertraline-induced mania, particularly in adolescent females.

Main Methods:

Case report detailing a patient experiencing manic symptoms after initiating sertraline treatment.
Review of existing literature on antidepressant-induced mania, focusing on SSRIs and adolescent populations.

Main Results:

The case presents a clear association between sertraline initiation and the onset of manic episode.
This finding contributes to the limited body of evidence on SSRI-induced mania.

Conclusions:

Sertraline, despite being an SSRI, can precipitate mania.
Caution is advised when prescribing sertraline to adolescent females, especially those with a predisposition to mood disorders.