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Metoclopramide to augment lactation, does it work? A randomized trial.

Shannon Fife¹, Prabhcharan Gill, Michael Hopkins

¹Department of Obstetrics and Gynecology, Aultman Health Foundation, Canton, Ohio, USA.

The Journal of Maternal-Fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians

|March 18, 2011

Summary

This summary is machine-generated.

Metoclopramide did not increase breast milk production in mothers of premature infants. Successful lactation relies on maternal support and education, not medication.

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Area of Science:

Neonatal Medicine
Pharmacology

Background:

Mothers of premature infants often face challenges with milk production.
Metoclopramide is sometimes used off-label to enhance lactation.

Purpose of the Study:

To evaluate the effectiveness of metoclopramide in augmenting milk production for mothers of preterm newborns.

Main Methods:

A randomized, double-blind, placebo-controlled trial was conducted.
Participants received either metoclopramide (10 mg three times daily) or placebo for 8 days.
Breast milk volume was recorded over the treatment period.

Main Results:

Milk production increased in both groups, but there was no significant difference between metoclopramide and placebo.
Average milk production for the last 4 days was 633 ml/day for placebo and 459 ml/day for metoclopramide.
No significant difference in milk production or side effects was observed between groups.

Conclusions:

Metoclopramide treatment does not augment breast milk production in mothers of preterm infants.
Maternal interest, education, and support are crucial for successful lactation.