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Modeling The Lifecycle Of Ebola Virus Under Biosafety Level 2 Conditions With Virus-like Particles Containing Tetracistronic Minigenomes
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A new Ebola virus nonstructural glycoprotein expressed through RNA editing

Masfique Mehedi1, Darryl Falzarano, Jochen Seebach

  • 1Department of Medical Microbiology, University of Manitoba, Public Health Agency of Canada, Winnipeg, Manitoba, Canada.

Journal of Virology
|March 18, 2011
PubMed
Summary

Researchers identified a new Ebola virus (EBOV) glycoprotein, small soluble glycoprotein (ssGP), produced by transcriptional editing. This ssGP, distinct from sGP, is N-glycosylated and forms homodimers but lacks sGP's anti-inflammatory function.

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