Hepatocellular adenomas: current update on genetics, taxonomy, and management
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Updated: Jun 3, 2026

A Three-Dimensional Spheroid Model to Investigate the Tumor-Stromal Interaction in Hepatocellular Carcinoma
Published on: September 30, 2021
Alampady Shanbhogue1, Shetal N Shah, Atif Zaheer
1Departments of Radiology, University of Texas Health Science Center at San Antonio, TX 78229, USA.
Abstract:
Hepatocellular adenomas (HCAs) are uncommon, benign hepatocellular neoplasms that commonly occur in young women. Recent advances in pathology and cytogenetics have thrown fresh light on the pathogenesis of HCAs leading to classification of HCAs into 3 distinct subtypes, each with a characteristic epidemiology, histopathology, oncogenesis, and imaging findings. The aim of the article was to provide a comprehensive review of contemporary taxonomy of HCAs, with an emphasis on cross-sectional imaging findings and management.
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