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Related Experiment Video

Updated: Jun 3, 2026

Microfluidic Chips Controlled with Elastomeric Microvalve Arrays
18:11

Microfluidic Chips Controlled with Elastomeric Microvalve Arrays

Published on: October 1, 2007

Flexible casting of modular self-aligning microfluidic assembly blocks.

Sean M Langelier1, Eric Livak-Dahl, Anthony J Manzo

  • 1Department of Chemical Engineering, University of Michigan, 2300 Hayward St. 3074 H.H. Dow Building, Ann Arbor, MI 48109-2136, USA.

Lab on a Chip
|March 18, 2011
PubMed
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This summary is machine-generated.

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This study introduces advanced modular microfluidic assembly blocks (MABs) for accessible device creation. These MABs simplify microfluidic fabrication, enabling complex applications without specialized facilities or expertise.

Area of Science:

  • Microfluidics
  • Biotechnology
  • Materials Science

Background:

  • Traditional clean-room microfabrication of microfluidic devices is complex and expensive.
  • There is a growing demand for accessible and user-friendly microfluidic tools.
  • Modular construction approaches offer a potential solution to these challenges.

Purpose of the Study:

  • To present an advanced modular microfluidic construction scheme using pre-fabricated microfluidic assembly blocks (MABs).
  • To enable rapid and easy fabrication of sophisticated microfluidic devices for diverse applications.
  • To overcome the limitations of traditional microfabrication methods.

Main Methods:

  • Development of a modular microfluidic assembly block (MAB) system.
  • Utilizing flexible casting trays for rapid MAB production and extraction.

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Published on: August 17, 2017

Scalable Fabrication of Stretchable, Dual Channel, Microfluidic Organ Chips
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Published on: October 20, 2018

Related Experiment Videos

Last Updated: Jun 3, 2026

Microfluidic Chips Controlled with Elastomeric Microvalve Arrays
18:11

Microfluidic Chips Controlled with Elastomeric Microvalve Arrays

Published on: October 1, 2007

Soft Lithographic Procedure for Producing Plastic Microfluidic Devices with View-ports Transparent to Visible and Infrared Light
10:26

Soft Lithographic Procedure for Producing Plastic Microfluidic Devices with View-ports Transparent to Visible and Infrared Light

Published on: August 17, 2017

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14:44

Scalable Fabrication of Stretchable, Dual Channel, Microfluidic Organ Chips

Published on: October 20, 2018

  • Employing pre-coated substrates for simultaneous assembly and bonding.
  • Incorporating automatic alignment and sealing structures into MAB design.

    • Main Results:

    • Demonstrated rapid production and assembly of MABs without specialized facilities or expertise.
    • Successfully created sophisticated microfluidic devices through a simplified construction scheme.
    • Showcased applications in chemical gradient synthesis, droplet generation, and total internal reflection fluorescence microscopy.

    Conclusions:

    • The advanced MAB system significantly lowers the barrier to entry for microfluidic device fabrication.
    • This modular approach facilitates the creation of complex microfluidic systems for various scientific and technological applications.
    • The developed MABs offer a versatile and accessible platform for microfluidic research and development.