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Updated: Jun 3, 2026
09:43
Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice
Published on: June 8, 2022
[Pregnancy in lupus patients: our experience]
A Giancotti1, A Spagnuolo, V D'ambrosio
1Dipartimento di Ginecologia ed Ostetricia, Universita degli studi di roma Sapienza, Policlinoco Umberto I Roma, Viale del Poloclinico, 155, 00161 Roma, Italia. antonellagiancotti@virgilio.it
Minerva Ginecologica
|March 18, 2011
Summary
Close monitoring of pregnancy in women with systemic lupus erythematosus (SLE) improves outcomes. This study highlights the importance of multidisciplinary care for managing SLE during pregnancy.
Area of Science:
- Obstetrics and Gynecology
- Rheumatology
- Maternal-Fetal Medicine
Context:
- Systemic lupus erythematosus (SLE) is a significant autoimmune condition impacting pregnancy.
- Managing SLE in pregnant individuals requires specialized care to mitigate risks.
- This study focuses on the outcomes of pregnancies complicated by SLE.
Purpose:
- To evaluate the management strategies for pregnancies affected by systemic lupus erythematosus (SLE).
- To assess the outcomes of pregnancies complicated by SLE.
- To identify factors influencing maternal and fetal well-being in SLE pregnancies.
Summary:
- The study involved 20 pregnant women with SLE, monitored from diagnosis to delivery.
- Outcomes included a 90% live birth rate, 50% preterm delivery, and a high incidence of small-for-gestational-age infants and intrauterine growth retardation (IUGR).
- Maternal disease activity and gestational hypertension were observed in 20% and 15% of patients, respectively.
Impact:
- Close obstetrical and ultrasound monitoring in a multidisciplinary setting can enhance pregnancy outcomes for women with SLE.
- Findings underscore the need for integrated care involving rheumatologists and maternal-fetal medicine specialists.
- Improved monitoring protocols can lead to better fetal growth and reduced rates of adverse neonatal outcomes.
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