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Updated: Jun 3, 2026

Normothermic Negative Pressure Ventilation Ex Situ Lung Perfusion: Evaluation of Lung Function and Metabolism
Published on: February 14, 2022
[Negative pressure pulmonary oedema and haemorrhage]
Jacek Majewski1, Ewa Górnik-Właszczuk, Bogdan Koczy
1Oddziat Anestezjologii i Intensywnej Terapii, Samodzielny Publiczny Wojewódzki Szpital Chirurgii Urazowej, Piekary Slaskie. sekretariat@urazowka.piekary.pl
Background:
Pulmonary haemorrhage due to negative airway pressure is a very rare but potentially fatal complication of general anaesthesia. Only a few such cases have been reported in the literature.
Case Report:
A previously healthy, 25-year-old man underwent general anaesthesia for internal stabilisation of a fractured clavicle. Shortly after extubation, he developed laryngospasm followed by pulmonary bleeding and acute respiratory failure. A CT-scan revealed acute pulmonary oedema. The patient was treated with mechanical ventilation and recovered completely after 72 hours.
Conclusion:
This rare complication may occur unexpectedly during routine anaesthesia. The rapid recognition and management of laryngospasm is essential.
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