Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

FISH - Fluorescent In-situ Hybridization02:07

FISH - Fluorescent In-situ Hybridization

Fluorescence in situ hybridization, or FISH, was developed in the early 1980s and has quickly become one of the most widely used techniques in cytogenetics. Labeled probes are used to bind complementary DNA or RNA sequences on a chromosome or in a region within a cell. Earlier, the probes could only be obtained by cloning or reverse transcription of a DNA template. Currently, the probe oligonucleotides can be synthesized synthetically. Additionally, with the advancement of optical techniques,...
Pharmacogenomics: Identification of New Drug Targets01:29

Pharmacogenomics: Identification of New Drug Targets

Advances in genomics have profoundly influenced drug discovery by increasing both the speed and accuracy of pharmaceutical development. Pharmacogenomics, which examines how genetic variation influences drug response, facilitates the identification of novel therapeutic targets and enables patient stratification for personalized treatment. These strategies contribute to improved drug efficacy, minimized adverse effects, and more efficient clinical trial design.Mapping genetic differences...
Genetic Screens02:46

Genetic Screens

Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing  genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which result in visible changes...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Time Course of Effects and Tissue Concentrations of 6PPDQ in Three Sensitive Salmonids with Additional Data for Two Centrarchid Species.

Environmental science & technology·2026
Same author

Roadway Runoff Induced Acute Mortality in Juvenile Coho Salmon During Spring Storm Events.

Environmental science & technology·2026
Same author

Safety and immunogenicity of investigational herpes simplex virus-2 vaccines in adults with recurrent genital infection.

Vaccine·2025
Same author

Evaluation of 6PPD-Quinone Lethal Toxicity and Sublethal Effects on Disease Resistance and Swimming Performance in Coastal Cutthroat Trout (<i>Oncorhynchus clarkii clarkii</i>).

Environmental science & technology·2025
Same author

Structurally Selective Ozonolysis of <i>p</i>-Phenylenediamines and Toxicity in Coho Salmon and Rainbow Trout.

Environmental science & technology·2024
Same author

Expansion of the HSV-2-specific T cell repertoire in skin after immunotherapeutic HSV-2 vaccine.

JCI insight·2024

Related Experiment Video

Updated: Jun 3, 2026

Mosaic Zebrafish Transgenesis for Functional Genomic Analysis of Candidate Cooperative Genes in Tumor Pathogenesis
09:45

Mosaic Zebrafish Transgenesis for Functional Genomic Analysis of Candidate Cooperative Genes in Tumor Pathogenesis

Published on: March 31, 2015

Fish T cells: recent advances through genomics.

Kerry J Laing1, John D Hansen

  • 1Vaccine and Infectious Diseases Division, Fred Hutchinson Cancer, Research Center, Seattle, WA 98109, USA.

Developmental and Comparative Immunology
|March 19, 2011
PubMed
Summary
This summary is machine-generated.

This review explores advances in fish T cell immunology, comparing teleost, elasmobranch, and agnathan fish to mammals. Fish possess key T cell components, with ongoing research enabling functional and phenotypic characterization.

More Related Videos

Modeling Tuberculosis in Mycobacterium marinum Infected Adult Zebrafish
07:00

Modeling Tuberculosis in Mycobacterium marinum Infected Adult Zebrafish

Published on: October 8, 2018

Isolating Malignant and Non-Malignant B Cells from lck:eGFP Zebrafish
08:32

Isolating Malignant and Non-Malignant B Cells from lck:eGFP Zebrafish

Published on: February 22, 2019

Related Experiment Videos

Last Updated: Jun 3, 2026

Mosaic Zebrafish Transgenesis for Functional Genomic Analysis of Candidate Cooperative Genes in Tumor Pathogenesis
09:45

Mosaic Zebrafish Transgenesis for Functional Genomic Analysis of Candidate Cooperative Genes in Tumor Pathogenesis

Published on: March 31, 2015

Modeling Tuberculosis in Mycobacterium marinum Infected Adult Zebrafish
07:00

Modeling Tuberculosis in Mycobacterium marinum Infected Adult Zebrafish

Published on: October 8, 2018

Isolating Malignant and Non-Malignant B Cells from lck:eGFP Zebrafish
08:32

Isolating Malignant and Non-Malignant B Cells from lck:eGFP Zebrafish

Published on: February 22, 2019

Area of Science:

  • Immunology
  • Comparative immunology
  • Fish biology

Background:

  • T cells are crucial for adaptive immunity in vertebrates.
  • Understanding T cell subsets and memory formation is key to immune response analysis.
  • Fish immunology provides insights into the evolution of vertebrate adaptive immunity.

Purpose of the Study:

  • To review current literature on T cell immunology in fish.
  • To compare T cell subset identification and memory cell differentiation in fish and mammals.
  • To highlight recent advances and future directions in fish T cell research.

Main Methods:

  • Comparative analysis of genomic data.
  • Review of literature on recombinant proteins and antibodies for T cell research.
  • Examination of T cell functional and phenotypic characterization studies.

Main Results:

  • Fish possess most components necessary for T cell function.
  • Putative T cell subsets and memory cell differentiation are suggested in fish.
  • Recombinant proteins and antibodies are available for studying teleost T cells.

Conclusions:

  • Significant progress has been made in fish T cell immunology.
  • Phenotypic and functional characterization of fish T cells is nearing realization.
  • Fish T cell research offers valuable comparative insights into vertebrate immunity.