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Focal epilepsy as first symptom in CADASIL

Reana Velizarova1, Isabelle Mourand, Anna Serafini

  • 1Epilepsy Unit, Gui de Chauliac Hospital, Montpellier, France.

Seizure
|March 19, 2011
PubMed

Insights

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL) can present with focal epilepsy. This case highlights new-onset seizures leading to a CADASIL diagnosis in a young woman without cognitive decline.

Area of Science:

  • Neurology
  • Neurogenetics
  • Epileptology

Background:

  • Cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL) is a genetic condition.
  • Principal symptoms include transient ischemic attacks, migraine, and dementia.
  • Epileptic seizures occur in approximately 10% of patients, often linked to ischemic stroke.

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