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Related Concept Videos

Cholera01:25

Cholera

Cholera is an acute gastrointestinal disease caused by the Gram-negative bacterium Vibrio cholerae. It is transmitted primarily via the fecal-oral route through the ingestion of contaminated water or food.Vibrio cholerae is a motile, Gram-negative bacterium of the family Vibrionaceae, primarily associated with waterborne outbreaks in areas with inadequate sanitation. Although over 200 serogroups of V. cholerae exist, only O1 and O139 are responsible for epidemic cholera. The O1 serogroup,...
Reservoir of Infection01:30

Reservoir of Infection

Infectious diseases arise from intricate interactions between pathogens and their reservoirs. A reservoir of infection refers to the natural habitat where a pathogen lives, grows, and multiplies, serving as a continual source of infection. Reservoirs are broadly classified as either living or nonliving, and each plays a unique role in disease transmission, significantly influencing public health interventions and control strategies.Humans act as reservoirs for a wide array of pathogens,...
Bacterial Gastroenteritis01:18

Bacterial Gastroenteritis

Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid receptor...
Bacterial Toxins01:12

Bacterial Toxins

Bacterial toxins are sophisticated virulence factors that enable pathogenic bacteria to interact with, invade, and damage host tissues. These toxins fall broadly into two types: protein exotoxins, which are secreted into the environment and target specific host receptors, and lipopolysaccharide endotoxins, which are structural components of the bacterial outer membrane released primarily during bacterial lysis or membrane shedding. Exotoxins generally act more selectively, binding to cell...
Stringent Response in E. coli01:23

Stringent Response in E. coli

Bacterial growth is closely tied to nutrient availability, with cells proliferating exponentially under favorable conditions and entering a stationary phase when resources become scarce. This transition is mediated by a regulatory mechanism known as the stringent response, which allows bacteria to adapt to nutrient deprivation by modulating gene expression and metabolic activity.During nutrient scarcity, intracellular amino acid levels decline. It results in the accumulation of uncharged tRNAs...
Transmission-based Precautions I: Contact, Enteric, and Droplets01:17

Transmission-based Precautions I: Contact, Enteric, and Droplets

Transmission-based precautions are for patients known to be infected or suspected to be infected or colonized with organisms that pose a significant risk to others. Some transmission-based precautions include contact, enteric, and droplet.
Contact Precautions:
Contact precautions are the measures taken to prevent the transmission of infectious agents, especially epidemiologically important microorganisms such as MRSA or influenza, primarily transmitted through direct or indirect contact with an...

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The Entner-Doudoroff pathway is obligatory for gluconate utilization and contributes to the pathogenicity of Vibrio cholerae.

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Related Experiment Video

Updated: Jun 3, 2026

Laboratory Techniques Used to Maintain and Differentiate Biotypes of Vibrio cholerae Clinical and Environmental Isolates
07:58

Laboratory Techniques Used to Maintain and Differentiate Biotypes of Vibrio cholerae Clinical and Environmental Isolates

Published on: May 30, 2017

Lessons from cholera & Vibrio cholerae.

Asoke C Ghose1

  • 1Department of Microbiology, Bose Institute, Kolkata, India. acghose@vsnl.net

The Indian Journal of Medical Research
|March 19, 2011
PubMed
Summary

Cholera, a severe diarrheal illness caused by Vibrio cholerae, has historically caused devastating epidemics. Research into this disease has led to significant biomedical discoveries and continues to be influenced by global socio-political factors.

Area of Science:

  • * Medical Microbiology
  • * Epidemiology
  • * Public Health

Background:

  • * Cholera is an acute diarrheal disease with a long history of causing devastating outbreaks.
  • * High mortality and morbidity rates have significantly impacted societies.
  • * The causative agent is the bacterium Vibrio cholerae.

Observation:

  • * Historical cholera outbreaks have had profound personal and social consequences.
  • * The severity of cholera spurred extensive scientific and clinical research.
  • * Research has led to major discoveries in biomedical sciences.

Findings:

  • * Investigating cholera and Vibrio cholerae has yielded significant scientific breakthroughs.
  • * These discoveries have opened new research avenues and scientific disciplines.

More Related Videos

Vibrio cholerae: Model Organism to Study Bacterial Pathogenesis - Interview
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Vibrio cholerae: Model Organism to Study Bacterial Pathogenesis - Interview

Published on: May 28, 2007

Quantifying Vibrio cholerae Colonization and Diarrhea in the Adult Zebrafish Model
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Quantifying Vibrio cholerae Colonization and Diarrhea in the Adult Zebrafish Model

Published on: July 12, 2018

Related Experiment Videos

Last Updated: Jun 3, 2026

Laboratory Techniques Used to Maintain and Differentiate Biotypes of Vibrio cholerae Clinical and Environmental Isolates
07:58

Laboratory Techniques Used to Maintain and Differentiate Biotypes of Vibrio cholerae Clinical and Environmental Isolates

Published on: May 30, 2017

Vibrio cholerae: Model Organism to Study Bacterial Pathogenesis - Interview
06:44

Vibrio cholerae: Model Organism to Study Bacterial Pathogenesis - Interview

Published on: May 28, 2007

Quantifying Vibrio cholerae Colonization and Diarrhea in the Adult Zebrafish Model
08:03

Quantifying Vibrio cholerae Colonization and Diarrhea in the Adult Zebrafish Model

Published on: July 12, 2018

  • * The study reviews key breakthroughs and their broader significance.

    • Implications:

    • * Understanding cholera's history informs current public health strategies.
    • * Scientific advancements have improved cholera diagnosis and treatment.
    • * Global socio-political conditions can influence cholera pandemicity and spread.