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Continuous Liquid-Liquid Extraction of Medium-Chain Fatty Acids from Fermentation Broth Using Hollow-Fiber Membranes

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Counter current "emulsion flow" extractor for continuous liquid-liquid extraction from suspended solutions.

Nobuyuki Yanase¹, Hirochika Naganawa, Tetsushi Nagano

¹Nuclear Science and Engineering Directorate, Japan Atomic Energy Agency, Tokai, Ibaraki, Japan. yanase.nobuyuki@jaea.go.jp

Analytical Sciences : the International Journal of the Japan Society for Analytical Chemistry

|March 19, 2011

Summary

A novel counter-current emulsion flow extractor prevents clogging by generating organic phase droplets. This overcomes limitations of previous designs for liquid-liquid extraction, enabling more robust applications.

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Area of Science:

Chemical Engineering
Separation Science
Fluid Dynamics

Background:

Traditional emulsion flow extractors face clogging issues due to particulate matter in the aqueous phase.
Micrometer-sized aqueous droplets spouting into an organic phase can obstruct apparatus holes.

Purpose of the Study:

To develop a more robust liquid-liquid extraction apparatus.
To overcome the clogging problem inherent in conventional emulsion flow extractors.

Main Methods:

Implementation of a counter-current flow design.
Generation of micrometer-sized organic phase droplets within an aqueous phase.

Main Results:

Successfully prevented clogging of the apparatus holes by particulate matter.
Demonstrated a functional counter-current emulsion flow extraction system.

Conclusions:

The counter-current emulsion flow extractor offers a viable solution to clogging issues.
This design enhances the practicality and reliability of emulsion flow liquid-liquid extraction.