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Full-Endoscopic Surgery for Hypothalamic Hamartoma Resection

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Isolated hemifacial hyperplasia.

Jintian Hu¹, Qiang Li, Bin Zhang

¹2nd Department, Plastic Surgery Hospital, Chinese Academy of Medical Sciences, Beijing, PR China.

The Journal of Craniofacial Surgery

|March 19, 2011

Summary

Hemifacial hyperplasia is a rare condition causing bone and soft tissue enlargement on one side of the face. This report details two pediatric cases, with surgical reconstruction used for a severe presentation.

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Isolating Hair Follicle Stem Cells and Epidermal Keratinocytes from Dorsal Mouse Skin

Isolating Hair Follicle Stem Cells and Epidermal Keratinocytes from Dorsal Mouse Skin

Published on: April 29, 2016

Area of Science:

Craniofacial Surgery
Pediatric Plastic Surgery
Medical Genetics

Background:

Hemifacial hyperplasia (HH), previously known as hemifacial hypertrophy, is a rare congenital condition.
It is characterized by the progressive, unilateral overgrowth of facial structures, including bone and soft tissues.
The etiology of HH remains largely unknown, though genetic and developmental factors are suspected.

Observation:

This report presents two pediatric cases diagnosed with hemifacial hyperplasia.
Case 1 involved significant unilateral facial enlargement affecting both skeletal and soft tissues.
Case 2 presented with a milder, yet noticeable, asymmetry.

Findings:

Both pediatric patients exhibited characteristic features of hemifacial hyperplasia.
The severe case necessitated surgical intervention for soft-tissue reconstruction to improve facial symmetry and function.
Conservative management was considered for the milder case, pending further observation.

Implications:

Early diagnosis and tailored management are crucial for optimizing outcomes in pediatric hemifacial hyperplasia.
Soft-tissue reconstruction techniques can effectively address the aesthetic and functional deficits in severe cases.
Further research into the genetic underpinnings of HH may lead to novel therapeutic strategies.