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Related Experiment Videos

Perianal dermatofibrosarcoma protuberans: a case report.

Orla Mc Cormack1, Ingrid S Heaslip, Manal Abdulrahim

  • 1Department of Surgery, Wexford General Hospital, Ireland. omccormack@rcsi.ie

Cutis
|March 22, 2011
PubMed
Summary
This summary is machine-generated.

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Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

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A rare perianal tumor, dermatofibrosarcoma protuberans (DFSP), was identified in a 67-year-old man. Surgical excision was challenging due to the tumor's deep extension and high recurrence rate, requiring further margin removal.

Area of Science:

  • Oncology
  • Dermatology
  • Surgical Pathology

Background:

  • Dermatofibrosarcoma protuberans (DFSP) is a rare, locally aggressive skin tumor.
  • DFSP typically presents on the trunk, making perianal locations uncommon.

Observation:

  • A 67-year-old male presented with a growing perianal lump.
  • Examination revealed a 3-cm irregular, polypoid mass at the anal verge.
  • Biopsy and immunohistochemistry (CD34 positive, epithelial markers negative) confirmed DFSP.

Findings:

  • Magnetic resonance imaging demonstrated deep extension into the ischiorectal space without sphincter involvement.
  • Initial excision with 1 cm margins and flap closure resulted in positive deep and lateral margins.
  • A wider excision achieved tumor-free margins.

Related Experiment Videos

Implications:

  • This case highlights a unique perianal presentation of DFSP.
  • Surgical management requires careful consideration of oncologic control, functional preservation, and cosmetic outcomes.
  • The high recurrence rate of DFSP necessitates thorough margin assessment and potentially wider resections.