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[Surgical treatment of early complications after ST-elevation myocardial infarction]
Carlo de Vincentiis1, Alessandro Varrica, Angela Satriano
1Dipartimento di Cardiochirurgia "E. Malan", IRCCS Policlinico San Donato, San Donato Milanese (MI). devince@libero.it
Insights
Cardiac rupture, a fatal myocardial infarction complication, affects 10-15% of in-hospital deaths. Early diagnosis and surgical repair are crucial for improving outcomes in patients experiencing hemodynamic deterioration.
Area of Science:
- Cardiology
- Cardiac Surgery
- Pathology
Context:
- Cardiac rupture is a life-threatening complication following myocardial infarction (MI).
- It accounts for 10-15% of in-hospital deaths after ST-elevation MI.
- Key risk factors include advanced age, female sex, first MI, and acute hypertension.
Purpose:
- To review the pathophysiology, risk factors, clinical presentation, and management of cardiac rupture.
- To highlight the critical role of early diagnosis and prompt surgical intervention.
- To discuss current surgical and percutaneous treatment strategies.
Summary:
- Cardiac rupture involves various heart structures, most commonly the left ventricular free wall.
- It typically occurs 4-7 days post-MI but can manifest earlier in specific patient profiles.
- Sudden hemodynamic deterioration is a key indicator, necessitating urgent diagnosis and stabilization.
- Surgical repair, including infartectomy with patch and glue, is the mainstay, with percutaneous options emerging for high-risk patients.
Impact:
- Early diagnosis and surgical treatment significantly improve survival rates for cardiac rupture.
- Understanding risk factors aids in identifying high-risk individuals for closer monitoring.
- Advancements in surgical and percutaneous techniques offer improved therapeutic options.
Abstract:
Cardiac rupture is a fatal complication of myocardial infarction that may involve especially the left ventricular free wall, the ventricular septum and the papillary muscle, but also the right ventricular free wall and more rarely the atrium. This complication is responsible for 10-15% of in-hospital deaths after ST-elevation myocardial infarction. Advanced age, female sex, first infarction and hypertension (in the acute phase of infarction) are the most important risk factors for cardiac rupture. It occurs typically between 4 and 7 days after the infarction but it may also develop within the first 24-48h, particularly in patients undergoing fibrinolytic therapy and in cardiac patients with the following characteristics: 1) recent coronary artery occlusion, 2) transmural necrosis, 3) poor collateral circulation, and 4) minimal or absent myocardial fibrosis. Cardiac rupture should be suspected when sudden or rapidly progressive hemodynamic deterioration occurs. After prompt diagnosis and stabilization, the patient can be operated. The high mortality rate between 5 and 14 days post-infarction justifies the urgency of surgical repair, which includes infartectomy and the employment of a Dacron patch and biological glues. Also percutaneous strategies have recently been used in patients with high surgical risk. The most frequently performed surgical techniques for the treatment of cardiac rupture are described below. By now early diagnosis and surgical treatment are crucial for successful outcome.
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