Childhood tinea incognito caused by Trichophyton mentagrophytes var. interdigitale mimicking pustular psoriasis

Yoshio Kawakami1, Noritaka Oyama1, Erika Sakai1

  • 1Department of Dermatology, Fukushima Medical University School of Medicine, Fukushima, Japan.

Pediatric Dermatology
|March 23, 2011
PubMed

Insights

Tinea incognito, a fungal infection altered by corticosteroids, presented as pustular psoriasis. Trichophyton mentagrophytes var. interdigitale was identified as the causative agent using genetic sequencing.

Area of Science:

  • Dermatology
  • Mycology
  • Medical Mycology

Background:

  • Tinea incognito describes fungal infections where clinical presentation is altered by corticosteroid use.
  • Corticosteroids can mask or worsen the symptoms of superficial fungal infections.

Observation:

  • A case of pustular psoriasis-like tinea incognito is presented.
  • The condition was caused by Trichophyton mentagrophytes var. interdigitale.

Findings:

  • Topical corticosteroid therapy aggravated the fungal infection, leading to a pustular psoriasis-like appearance.
  • Molecular identification using internal transcribed spacer 2 and D1D2 domain sequencing confirmed the fungal species.

Implications:

  • Accurate identification of fungal species is crucial for effective treatment of tinea incognito.
  • Understanding the impact of corticosteroids on fungal infections aids in diagnosis and management.
  • Genetic sequencing provides a reliable method for identifying dermatophytes causing atypical presentations.

Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
The Skin Microbiota01:27

The Skin Microbiota

The human skin serves as a complex ecosystem inhabited by a diverse community of microorganisms, including bacteria, fungi, and viruses. This microbiome plays a critical role in maintaining skin health and defending against pathogenic invaders. The composition of microbial communities varies significantly across different regions of the body, influenced primarily by the local levels of moisture and sebum.Regional Variation in Skin MicrobiotaCutibacterium acnes predominantly colonizes sebaceous...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Papillary Dermis01:11

Papillary Dermis

Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...
Trichomoniasis01:18

Trichomoniasis

Trichomonas vaginalis is a flagellated protozoan parasite and the causative agent of trichomoniasis, one of the most prevalent non-viral sexually transmitted infections in the United States. This extracellular parasite primarily colonizes the lower genitourinary tract in women—particularly the vagina—and in men, the urethra and prostate. Its structural and functional adaptations enable its survival, motility, and pathogenicity within the host environment.Structural Features and Host EntryT.