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Type of milk feeding affects hematological parameters and serum lipid profile in Japanese infants

Haruhiko Isomura1, Hidemi Takimoto, Fumihiro Miura

  • 1Department of Health Promotion, National Institute of Public Health, Wako, Japan.

Pediatrics International : Official Journal of the Japan Pediatric Society
|March 23, 2011
PubMed

Insights

Japanese infants fed breast milk showed higher anemia risk at six months, while formula-fed infants had lower serum lipid levels. Iron-fortified foods and improved formula fat quality are recommended.

Area of Science:

  • Pediatrics
  • Nutrition Science
  • Infant Health

Background:

  • Infant feeding type and volume significantly impact growth, hematological parameters, and serum lipids.
  • Understanding these effects is crucial for optimizing infant nutrition and health outcomes.

Purpose of the Study:

  • To investigate the relationship between infant feeding methods (breast milk vs. formula) and key health indicators at 1 and 6 months of age.
  • To identify potential nutritional deficiencies or imbalances associated with different feeding practices in Japanese infants.

Main Methods:

  • A cohort of 103 healthy term infants with birthweights >2200g was studied.
  • Milk intake, anthropometry, hematological tests, and serum lipid profiles were assessed at 1 and 6 months.
  • Infants were categorized as breast-fed, partially breast-fed, or formula-fed at 6 months.

Main Results:

  • Breast-fed infants exhibited similar growth to formula-fed infants despite lower milk intake.
  • Higher breast milk intake correlated with lower hemoglobin levels (anemia risk).
  • Higher formula intake correlated with lower serum total cholesterol levels.

Conclusions:

  • Japanese breast-fed infants were more prone to anemia at 6 months.
  • Formula-fed infants were more likely to have low serum lipid levels.
  • Recommendations include iron-fortified foods for breast-fed infants and improved fat quality in formulas.
Abstract

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