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Gastrointestinal relapse of multiple myeloma and sustained response to lenalidomide: a case report
Patrick R Benusiglio1, Thomas A McKee, Xavier Montet
1Centre for Oncology, Geneva University Hospital, 4 rue Gabrielle Perret-Gentil, 1211 Geneva 14, Switzerland. Patrick.Benusiglio@hcuge.ch.
Introduction:
Gastrointestinal relapse in patients with multiple myeloma is very rare and, when reported, always associated with a poor prognosis.
Case Presentation:
We describe the case of a 71-year-old Caucasian man who presented with life-threatening hematemesis and melena due to a digestive relapse of his multiple myeloma. Despite the active hemorrhage, we initiated a third-line treatment with lenalidomide. The response was spectacular and long-lasting.
Conclusions:
Clinicians must consider digestive tract involvement in myeloma patients presenting with a gastrointestinal hemorrhage. Furthermore, myeloma patients do benefit from novel oral drugs, even when they are critically ill.
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