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Related Experiment Video

Updated: Jun 3, 2026

Synthesis of Core-shell Lanthanide-doped Upconversion Nanocrystals for Cellular Applications
13:51

Synthesis of Core-shell Lanthanide-doped Upconversion Nanocrystals for Cellular Applications

Published on: November 10, 2017

Upconversion nanoparticles: synthesis, surface modification and biological applications.

Meng Wang1, Gopal Abbineni, April Clevenger

  • 1College of Sciences, Northeastern University, Shenyang, People's Republic of China.

Nanomedicine : Nanotechnology, Biology, and Medicine
|March 23, 2011
PubMed
Summary
This summary is machine-generated.

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Upconversion nanoparticles (UCNPs) are novel fluorophores converting near-infrared to visible light. Their unique properties offer advanced solutions for biological imaging and biodetection assays.

Area of Science:

  • Nanotechnology
  • Materials Science
  • Biomedical Engineering

Background:

  • Upconversion nanoparticles (UCNPs) represent a new generation of fluorophores.
  • They utilize nonlinear optical processes to convert lower-energy near-infrared radiation into higher-energy visible radiation.
  • UCNPs are emerging as promising alternatives to traditional fluorescent labels for various applications.

Purpose of the Study:

  • To review recent advancements in the synthesis and surface modification of rare-earth doped UCNPs.
  • To highlight the expanding biological applications of UCNPs.
  • To discuss the advantages of UCNPs over conventional fluorescent probes.

Main Methods:

  • Synthesis of rare-earth doped UCNPs.
  • Surface modification techniques for UCNPs.

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Harmonic Nanoparticles for Regenerative Research
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Harmonic Nanoparticles for Regenerative Research

Published on: May 1, 2014

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Last Updated: Jun 3, 2026

Synthesis of Core-shell Lanthanide-doped Upconversion Nanocrystals for Cellular Applications
13:51

Synthesis of Core-shell Lanthanide-doped Upconversion Nanocrystals for Cellular Applications

Published on: November 10, 2017

Harmonic Nanoparticles for Regenerative Research
09:23

Harmonic Nanoparticles for Regenerative Research

Published on: May 1, 2014

  • Evaluation of UCNP properties for biological applications.

    • Main Results:

    • UCNPs possess unique luminescent properties, including high tissue penetration depth and resistance to photobleaching.
    • They offer low background signals and large Stokes shifts, enhancing imaging sensitivity.
    • UCNPs demonstrate significant potential in both in vitro and in vivo imaging and biodetection.

    Conclusions:

    • UCNPs offer superior performance compared to traditional fluorescent probes.
    • Their unique optical and physical properties make them highly suitable for advanced biological applications.
    • Continued research in UCNP synthesis and modification will further expand their utility in biomedical fields.