Related Experiment Video
Updated: Jun 3, 2026

Visualization of Streptococcus pneumoniae within Cardiac Microlesions and Subsequent Cardiac Remodeling
Published on: April 7, 2015
Evolution of vegetation size in left-sided endocarditis. Is it a prognostic factor during hospitalization?
Carmen Manzano1, Isidre Vilacosta, Cristina Fernández
1Instituto Cardiovascular, Hospital Universitario San Carlos, Madrid, Spain.
Abstract:
The objective was to describe the vegetation changes in patients with endocarditis and evaluate their prognostic importance during hospitalization. We selected patients with left-sided endocarditis and two transesophageal echocardiograms separated by at least 8 days. Patients who required surgery or died during the first week after diagnosis of the disease were excluded. Patients were classified into three groups: I, patients whose vegetation increased in size (n=34); II, patients with vegetations that did not vary in size (n=62); and III, patients whose vegetation decreased in size (n=59). Patients whose vegetation increased in size more frequently required surgery. Multivariate analysis showed that the increase in the vegetation is independently associated with increased mortality: adjusted odds ratio, 4.12 (95% confidence interval, 1.14-14.9; P=.031).
Related Concept Videos
Endocarditis III: Medical Management
Endocarditis II: Clinical Features of Infective Endocarditis
Endocarditis I: Introduction
Endocarditis IV: Nursing Management
Aortic Regurgitation II: Clinical Features and Diagnostic Tests
Myocarditis III: Medical Management