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Updated: Jun 3, 2026
06:15
Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
Cutaneous squamous cell carcinoma arising within generalised morphea.
Daniel B Saleh1, Andrew M Williams, Ian M Smith
1Plastic and Reconstructive Surgery, Leeds General Infirmary, Great George Street, Leeds LS1 3EX, UK. dan_saleh@hotmail.com
Summary
Morphea, a form of localized scleroderma, typically involves benign skin inflammation. This case highlights squamous cell carcinoma developing within a morphoea plaque, necessitating aggressive treatment.
Area of Science:
- Dermatology
- Oncology
- Pathology
Background:
- Morphea, a subtype of localized scleroderma, is characterized by benign cutaneous inflammation.
- Squamous cell carcinoma (SCC) is a common skin cancer, but its occurrence within morphoea is rare.
Observation:
- A patient presented with a morphoeic plaque, a characteristic lesion of morphea.
- Cutaneous squamous cell carcinoma was diagnosed within this morphoeic plaque.
Findings:
- The study documents an unusual case of squamous cell carcinoma arising in a morphoea lesion.
- Histopathological confirmation of malignancy within the benign inflammatory skin condition was established.
Implications:
- This case underscores the importance of vigilant monitoring for secondary malignancies in chronic skin conditions like morphea.
- The rationale for aggressive treatment strategies in such rare, complex presentations is discussed, aiming to improve patient outcomes.
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