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Related Concept Videos

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Related Experiment Video

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A Cognitive Paradigm to Investigate Interference in Working Memory by Distractions and Interruptions
10:38

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Published on: July 16, 2015

Modulation of working-memory maintenance by directed attention.

Jöran Lepsien1, Ian Thornton, Anna C Nobre

  • 1Brain & Cognition Laboratory, Department of Experimental Psychology, University of Oxford, United Kingdom. lepsien@cbs.mpg.de

Neuropsychologia
|March 23, 2011
PubMed
Summary

Directed attention dynamically modulates working memory (WM) content. Orienting attention to specific stimulus categories, like faces or scenes, enhances their neural representation in the brain, aiding future behavior.

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Last Updated: Jun 3, 2026

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Area of Science:

  • Cognitive Neuroscience
  • Neuroimaging

Background:

  • Working memory (WM) models often link WM capacity to attention.
  • Attention can be voluntarily directed towards items within WM, potentially influencing their maintenance.

Purpose of the Study:

  • To investigate how directing attention to a specific stimulus category affects neural representations during WM maintenance.
  • To examine the role of extrastriate and associative brain regions in attention-modulated WM.

Main Methods:

  • Event-related functional magnetic resonance imaging (fMRI) was employed.
  • Participants maintained varying numbers of faces and scenes in WM.
  • Retro-cues indicated the relevant stimulus category for a subsequent test.

Main Results:

  • Retro-cues modulated activity in category-selective extrastriate areas (fusiform and parahippocampal gyri) in a categorical manner.
  • Activity in these areas increased for the cued category, independent of WM load.
  • Modulation was also observed in associative parietal and prefrontal cortices, correlating with the number of maintained items.

Conclusions:

  • Attention flexibly modulates WM representations in a goal-directed manner.
  • Extrastriate areas show category-specific maintenance modulation.
  • Associative cortices play a role in flexible WM maintenance and guiding behavior.