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Anti-HBs response in seroconverting chronic HBV carriers following alpha-interferon treatment
P Karayiannis1, S Kanatakis, H C Thomas
1Department of Medicine, St. Mary's Hospital Medical School, Imperial College of Science, Technology and Medicine, London, United Kingdom.
Abstract:
The antibody response to hepatitis B surface antigen (anti-HBs) was studied in 15 chronic hepatitis B virus (HBV)-infected patients who seroconverted following treatment with alpha interferon. The levels of anti-HBs (IU/l) attained were significantly lower than those recorded in patients with convalescent symptomatic or asymptomatic acute infection and in hospital personnel who received a plasma derived HBV vaccine.
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