Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Sexually Transmitted Infections01:26

Sexually Transmitted Infections

Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
Larynx01:21

Larynx

The human larynx, often referred to as the voice box, is an intricate organ located in the neck. It serves as a pathway for air to enter the lungs during respiration and is an essential component of voice production.
Anatomy of the Larynx
The larynx consists of various components, including cartilage, muscles, and vocal cords. Its structure includes three large unpaired cartilages—the thyroid, cricoid, and epiglottis—and three smaller paired cartilages—the arytenoids, corniculates, and...
Streptococcal Pharyngitis01:27

Streptococcal Pharyngitis

Streptococcal pharyngitis, commonly known as “strep throat,” is an acute infection of the oropharyngeal tissues caused by the Gram‑positive Group A Streptococcus (Streptococcus pyogenes). Transmission occurs primarily through respiratory droplets expelled during coughing, sneezing, or talking.Mechanisms of Host Entry and Immune EvasionUpon entering the host, S. pyogenes adheres to the mucosal epithelial cells of the pharynx via surface proteins, notably lipoteichoic acid and the antiphagocytic...
Acute Pharyngitis01:30

Acute Pharyngitis

Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
Chronic Pharyngitis01:23

Chronic Pharyngitis

Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
Tonsillitis I: Introduction01:30

Tonsillitis I: Introduction

Tonsillitis is inflammation of the tonsils, which are two lymphoid tissue masses at the back of the throat. This condition can cause discomfort and irritation in the throat.
Etiology
Three primary contributing factors have been identified.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Arytenoid Cartilage Ossification in Early Glottic Carcinoma and Its Association With Tumour Stage and Treatment Outcome: A Retrospective Analysis.

Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·2026
Same author

The impact of surgery type on the recovery of iatrogenic vocal fold injury.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·2026
Same author

Acute mastoiditis-associated cerebral sinus venous thrombosis in children: a retrospective review.

European journal of pediatrics·2025
Same author

Risk Stratification and Long-Term Outcome of Benign Thyroid Nodules - An 11-Year Cohort Study.

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·2025
Same author

Can the Repetitive Saliva Swallow Test Predict Airway Invasion in All Cause Dysphagia?

The Laryngoscope·2025
Same author

Predictors of Pneumonia in Patients With Penetration-Aspirations Detected on Fiberoptic Endoscopic Evaluation of Swallowing.

Dysphagia·2025
Same journal

Pathology quiz case 2.

Archives of otolaryngology--head & neck surgery·2014
Same journal

Pathology quiz case 1.

Archives of otolaryngology--head & neck surgery·2014
Same journal

Radiology quiz case 1: diagnosis.

Archives of otolaryngology--head & neck surgery·2013
Same journal

Pair of red and green macaws.

Archives of otolaryngology--head & neck surgery·2013
Same journal

Pathology quiz case 2: diagnosis.

Archives of otolaryngology--head & neck surgery·2013
Same journal

About this journal.

Archives of otolaryngology--head & neck surgery·2013
See all related articles

Related Experiment Video

Updated: Jun 3, 2026

Learning Modern Laryngeal Surgery in a Dissection Laboratory
07:30

Learning Modern Laryngeal Surgery in a Dissection Laboratory

Published on: March 18, 2020

Laryngeal syphilis: a case report.

Gil Lahav1, Yonatan Lahav, Pnina Ciobotaro

  • 1Department of Otolaryngology Head and Neck Surgery, Kaplan Medical Center, PO Box 1, Rehovot, 76600 Israel. gillah@clalit.org.il

Archives of Otolaryngology--Head & Neck Surgery
|March 23, 2011
PubMed
Summary
This summary is machine-generated.

Syphilis, a complex sexually transmitted disease, can severely damage the larynx. Historical records show a case of syphilis-induced laryngeal destruction in 1866, predating early laryngectomy reports.

Related Experiment Videos

Last Updated: Jun 3, 2026

Learning Modern Laryngeal Surgery in a Dissection Laboratory
07:30

Learning Modern Laryngeal Surgery in a Dissection Laboratory

Published on: March 18, 2020

Area of Science:

  • Medical History
  • Infectious Diseases
  • Otolaryngology

Background:

  • Syphilis, caused by Treponema pallidum, is a complex sexually transmitted infection known for its diverse clinical manifestations.
  • William Osler famously stated, "He who knows syphilis, knows medicine," highlighting its broad impact on internal medicine.

Observation:

  • A historical report from 1866 details a case where syphilis led to the complete destruction of a 36-year-old man's larynx.
  • This diagnosis was confirmed postmortem, underscoring the advanced stage of the disease at the time of examination.

Findings:

  • The 1866 case of laryngeal destruction due to syphilis was previously misattributed as the first total laryngectomy.
  • Historical analysis reveals that Christian Albert Theodor Billroth performed the first documented total laryngectomy in 1873 for laryngeal carcinoma.

Implications:

  • This historical case highlights the severe, destructive potential of untreated syphilis, particularly its impact on the upper airway.
  • Understanding such historical medical cases provides valuable context for the evolution of surgical procedures and the recognition of complex disease presentations.
  • The distinction between syphilis-induced laryngeal destruction and surgical laryngectomy is crucial for accurate medical history and understanding treatment advancements.